73627-18-6

Basic information

• Product Name: 1-METHYL-1,2,3,4-TETRAHYDRO-PYRROLO[1,2-A]PYRAZINE
• Synonyms: 1,2,3,4-Tetrahydro-1-methylpyrrolo[1,2-a]pyrazine;1-methyl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine(SALTDATA: HCl 0.1H2O)
• CAS NO: 73627-18-6
• Molecular Formula: C8H12N2
• Molecular Weight: 136.2
• Mol File: 73627-18-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 243.4°C at 760 mmHg
• Flash Point: 101°C
• Appearance: /
• Vapor Pressure: 0.0322mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 1-METHYL-1,2,3,4-TETRAHYDRO-PYRROLO[1,2-A]PYRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-1,2,3,4-TETRAHYDRO-PYRROLO[1,2-A]PYRAZINE(73627-18-6)
• EPA Substance Registry System: 1-METHYL-1,2,3,4-TETRAHYDRO-PYRROLO[1,2-A]PYRAZINE(73627-18-6)

Safety Data

• Hazardous Substances Data: 73627-18-6(Hazardous Substances Data)

Usage

General Description

1-METHYL-1,2,3,4-TETRAHYDRO-PYRROLO[1,2-A]PYRAZINE, also known as norharmane, is a chemical compound with the molecular formula C8H10N2. It is a heterocyclic amine and a derivative of pyrrole that is commonly found in plants, tobacco smoke, and certain foods. Norharmane has been identified as a potential mutagen and carcinogen, and it has been linked to the development of certain cancers. It is also a psychoactive compound that can affect neurotransmitter levels in the brain. Norharmane is used in research and pharmaceutical applications and is a subject of ongoing study for its potential health effects.

InChI:InChI=1/C8H12N2/c1-7-8-3-2-5-10(8)6-4-9-7/h2-3,5,7,9H,4,6H2,1H3/p+1/t7-/m1/s1

Upstream product

• 1192-62-7 1-(2-furyl)-1-ethanone 
• 107-15-3 ethylenediamine 
• 64608-66-8 1-methyl-3,4-dihydropyrrolo[1,2-a]pyrazine 
• 73627-16-4 N-[2-(1H-pyrrol-1-yl)ethyl]acetamide 

Downstream Products

• 1174283-09-0 N-(2-(2-(1-tert-butyl-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)-N,2,4,6-tetramethylbenzenesulfonamide 
• 1174282-70-2 4-methoxy-N,2,3,6-tetramethyl-N-(2-(2-(1-methyl-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)benzenesulfonamide 
• 1174283-11-4 N,2,4,6-tetramethyl-N-(2-(2-oxo-2-(1-(pyridin-3-yl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide 
• 1174282-63-3 N-(2-(2-(5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)-2-oxoethoxy)ethyl)-N-isobutyl-4-methoxy-2,3,6-trimethylbenzenesulfonamide 
• 1174282-88-2 N-benzyl-4-methoxy-2,6-dimethyl-N-(2-(2-(1-methyl-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)benzenesulfonamide 
• 1174283-17-0 N-(2-(2-(1-(3-fluorophenyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)-N,2,4,6-tetramethylbenzenesulfonamide 
• 1174282-82-6 N-benzyl-4-methoxy-2,3,6-trimethyl-N-(2-(2-(1-methyl-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)benzenesulfonamide 
• 1174283-06-7 4-methoxy-N-(2-(2-(1-(3-methoxyphenyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)-N,2,6-trimethylbenzenesulfonamide 
• 1174282-85-9 N-benzyl-N-(2-(2-(5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)-2-oxoethoxy)ethyl)-4-methoxy-2,3,6-trimethylbenzenesulfonamide 
• 1174282-72-4 N-(2-(2-(1-(6-chloropyridin-3-yl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)-4-methoxy-N,2,3,6-tetramethylbenzenesulfonamide 
• 1174283-01-2 N-(2-(2-(1-(3,4-difluorophenyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)-4-methoxy-N,2,6-trimethylbenzenesulfonamide 
• 1174282-60-0 N-isobutyl-4-methoxy-2,3,6-trimethyl-N-(2-(2-oxo-2-(1-(pyridin-3-yl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide 
• 1174283-08-9 N-(2-(2-(1-(4-tert-butylphenyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)-4-methoxy-N,2,6-trimethylbenzenesulfonamide 
• 1174282-58-6 N-(2-(2-(6-((dimethylamino)methyl)-1-(thiophen-2-yl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)-4-methoxy-N,2,6-trimethylbenzene-sulfonamide 

Relevant articles and documents

1,2,3,6-Tetrahydropyrrolo[1,2-d][1,4]diazocines. Reactions of 1-methyl-2-R-tetrahydropyrrolo[1,2-a]pyrazines with alkynes

The reactions of 6-formyl-and 6-trifluoroacetyl-1-methyl-2-R- tetrahydropyrrolo[1,2-a]- pyrazines with activated alkynes in methanol and acetonitrile have been studied. Terahydro- pyrrolo[1,2-d][1,4]diazocine derivatives were synthesized at the first time.

SUBSTITUTED SULFONAMIDE DERIVATIVES

The invention relates to substituted sulfonamide derivatives of the general formula (I'); processes for their preparation, medicaments containing these compounds, and the use of substituted sulfonamide derivatives for the preparation of medicaments

AZACYCKLOALKANES. XXX. PYRROLOPYRAZINES WITH VARIABLE DEGREES OF PYRAZINE RING SATURATION AND THEIR HYPOTENSIVE ACTIVITY

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