73696-35-2

Basic information

• Product Name: 5,6,7,8-Tetrahydro-2-phenyl-4H-[1]benzothieno[2,3-d][1,3]oxazin-4-one
• Synonyms: 5,6,7,8-Tetrahydro-2-phenyl-4H-[1]benzothieno[2,3-d][1,3]oxazin-4-one;5,6,7,8-Tetrahydro-2-phenyl-4H-[1]benzothieno[2,3-d][1,3]oxazin-4-one
• CAS NO: 73696-35-2
• Molecular Formula: C₁₆H₁₃NO₂S
• Molecular Weight: 283.35
• Mol File: 73696-35-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 138-140 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 462.6±34.0 °C(Predicted)
• Appearance: /
• Density: 1.42±0.1 g/cm3(Predicted)
• PKA: 0.68±0.20(Predicted)
• CAS DataBase Reference: 5,6,7,8-Tetrahydro-2-phenyl-4H-[1]benzothieno[2,3-d][1,3]oxazin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6,7,8-Tetrahydro-2-phenyl-4H-[1]benzothieno[2,3-d][1,3]oxazin-4-one(73696-35-2)
• EPA Substance Registry System: 5,6,7,8-Tetrahydro-2-phenyl-4H-[1]benzothieno[2,3-d][1,3]oxazin-4-one(73696-35-2)

Safety Data

• Hazardous Substances Data: 73696-35-2(Hazardous Substances Data)

Usage

General Description

5,6,7,8-Tetrahydro-2-phenyl-4H-[1]benzothieno[2,3-d][1,3]oxazin-4-one is a chemical compound with a complex molecular structure. It is classified as a heterocyclic compound, containing both nitrogen and oxygen atoms in its ring system. This chemical is a member of the benzothiophene family and has a phenyl group attached to its carbon atoms. It is used in various organic synthesis reactions and pharmaceutical research as a building block for the creation of novel compounds with potential biological activity. Its unique structure and reactivity make it a valuable tool for medicinal chemistry and drug discovery efforts.

Upstream product

• 52580-57-1 2-benzamide-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ethyl ester 
• 52535-73-6 4,5,6,7-tetrahydrobenzothiophene-2-benzoylamino-3-carboxylic acid 
• 98-88-4 benzoyl chloride 
• 90543-03-6 4,5,6,7-Tetrahydro-2-(triphenylphosphoranylidenamino)benzothiophen-3-carbonsaeure-ethylester 
• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 108-94-1 cyclohexanone 
• 5936-58-3 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid 

Downstream Products

• 78033-86-0 2-Benzoylamino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid propyl ester 
• 78033-88-2 2-Benzoylamino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid 2-dimethylamino-ethyl ester 
• 78033-90-6 2-Benzoylamino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid 3-dimethylamino-propyl ester 
• 73696-42-1 2-benzamido-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbohydrazide 
• 63274-56-6 2-phenyl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d][1,3]thiazine-4-thione 
• 78033-87-1 2-Benzoylamino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid 2-hydroxy-ethyl ester 
• 108561-29-1 4-(diethylamino)-5,6,7,8-tetrahydro-3-methyl-2-phenylbenzo<4,5>thieno<2,3-b>pyridine 
• 78033-89-3 2-Benzoylamino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid 2-diethylamino-ethyl ester 
• 105544-23-8 3-Methyl-2-phenyl-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidine-4-thione 
• 63274-59-9 2-phenyl-5,6,7,8-tetrahydro-4H-benzothieno[2,3-d][1,3]thiazin-4-one 
• 356586-88-4 N-[3-(piperidine-1-carbonyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-2-yl]benzamide 
• 312948-88-2 C₂₀H₂₂N₂O₃S 
• 35149-36-1 2-phenyl-4-methoxy-5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidine 
• 35149-32-7 4-chloro-2-phenyl-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidine 

Relevant articles and documents

Synthesis of some new tetrahydrobenzo[b] thiophene derivatives and tetrahydrobenzo-thienopyrimidine derivatives under microwave irradiation

2-Phenyl-5,6,7,8-tetrahydro-4H-benzothieno[2,3-d][1,3]oxazin-4-one (4) was reacted with either aliphatic or aromatic primary amines such as benzylamine, cyclohexylamine, p-toluidine, and=or p-anisidine to give carboxamide derivatives 5a-d, respectively. A

Heterocyclic β-Enamino Esters, 27. Synthesis of Heterocondensed 6H-1,3-Oxazin-6-ones from N-Acylenamino Esters in the System Triphenylphosphane/Hexachloroethane/Triethylamine

A simple ring closure reaction of N-acylenamino esters (1b, e, 2, 3a - f, 7) in the system triphenylphosphane/hexachloroethane/triethylamine is described proceeding with high yields.Under chlorinating 3-ester cleavage heterocondensed 6H-1,3-oxazin-6-ones