736987-75-0 Usage
Description
E-2-(Thiophen-3-yl)vinylboronic acid pinacol ester is a chemical compound that belongs to the boronic acid ester family. It features a vinylboronic acid group attached to a thiophene ring, along with a pinacol ester functional group. E-2-(Thiophen-3-yl)vinylboronic acid pinacol ester is known for its unique structure and reactivity, which makes it a valuable tool in various fields.
Uses
Used in Organic Synthesis:
E-2-(Thiophen-3-yl)vinylboronic acid pinacol ester is used as a reagent in organic synthesis for the formation of carbon-carbon bonds through cross-coupling reactions. Its distinctive structure and reactivity contribute to its effectiveness in this application.
Used in Pharmaceutical Development:
In the pharmaceutical industry, E-2-(Thiophen-3-yl)vinylboronic acid pinacol ester is utilized as a key intermediate in the synthesis of various drug molecules. Its ability to form carbon-carbon bonds makes it instrumental in creating complex molecular structures necessary for new medications.
Used in Agrochemicals:
E-2-(Thiophen-3-yl)vinylboronic acid pinacol ester also finds application in the agrochemical sector, where it serves as a building block for the development of new pesticides and other agricultural chemicals. Its role in creating carbon-carbon bonds is crucial for the synthesis of these compounds.
Used in Materials Science:
In the field of materials science, E-2-(Thiophen-3-yl)vinylboronic acid pinacol ester is employed in the synthesis of advanced materials with specific properties. Its contribution to the formation of carbon-carbon bonds aids in the development of materials with tailored characteristics for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 736987-75-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,3,6,9,8 and 7 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 736987-75:
(8*7)+(7*3)+(6*6)+(5*9)+(4*8)+(3*7)+(2*7)+(1*5)=230
230 % 10 = 0
So 736987-75-0 is a valid CAS Registry Number.
736987-75-0Relevant articles and documents
Hexamethyldisilazane Lithium (LiHMDS)-Promoted Hydroboration of Alkynes and Alkenes with Pinacolborane
Liu, Jichao,Wu, Caiyan,Hu, Tinghui,Yang, Wei,Xie, Yaoyao,Shi, Yinyin,Liu, Qianrui,Shao, Yinlin,Zhang, Fangjun
, p. 3442 - 3452 (2022/02/23)
Lithium-promoted hydroboration of alkynes and alkenes using commercially available hexamethyldisilazane lithium as a precatalyst and HBpin as a hydride source has been developed. This method will be appealing for organic synthesis because of its remarkable substrate tolerance and good yields. Mechanistic studies revealed that the hydroboration proceeds through the in situ-formed BH3species, which acts to drive the turnover of the hydroboration of alkynes and alkenes.
Selective hydroboration of alkynes via multisite synergistic catalysis by PCN-222(Cu)
Ma, L. J.,Tang, Z. Y.,Yuan, J. C.,Zhang, L. J.,Zhang, X. M.
, p. 63 - 69 (2021/08/03)
Zirconium-based porphyrinic MOFs (PMOFs, MOF = metal-organic framework) have gained considerable attention in the field of electric/thermo/photo-catalysis as heterogeneous single-site catalysts; however, the study on multisite synergistic catalysis of PMO
Enantioselective Copper-Catalyzed Synthesis of Trifluoromethyl-Cyclopropylboronates
Altarejos, Julia,Carreras, Javier,Sucunza, David,Vaquero, Juan J.
supporting information, p. 6174 - 6178 (2021/08/18)
A copper-catalyzed enantioselective cyclopropanation involving trifluorodiazoethane in the presence of alkenyl boronates has been developed. This transformation enables the preparation of 2-substituted-3-(trifluoromethyl)cyclopropylboronates with high levels of stereocontrol. The products are valuable synthetic intermediates by transformation of the boronate group. This methodology can be applied to the synthesis of novel trifluoromethylated analogues of trans-2-arylcyclopropylamines, which are prevalent motifs in biologically active compounds.
