736987-78-3

Basic information

• Product Name: E-2-(2 4-DIFLUOROPHENYL)VINYLBORONIC AC&
• Synonyms: trans-2-(2,4-Difluorophenyl)vinylboronic acid pinacol ester 96%;E-2-(2 4-DIFLUOROPHENYL)VINYLBORONIC;E-2-(2 4-DIFLUOROPHENYL)VINYLBORONIC AC&;E-2-(2,4-Difluorophenyl)vinylboronic acid, pinacol ester;(E)-2-(2,4-Difluorostyryl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane;2-[(E)-2-(2,4-difluorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 736987-78-3
• Molecular Formula: C₁₄H₁₇BF₂O₂
• Molecular Weight: 266.093
• Mol File: 736987-78-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 103-105 °C0.2-0.3 mm Hg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.099 g/mL at 25 °C
• Vapor Pressure: 0.0129mmHg at 25°C
• Refractive Index: n20/D 1.503
• Storage Temp.: 2-8°C
• CAS DataBase Reference: E-2-(2 4-DIFLUOROPHENYL)VINYLBORONIC AC&(CAS DataBase Reference)
• NIST Chemistry Reference: E-2-(2 4-DIFLUOROPHENYL)VINYLBORONIC AC&(736987-78-3)
• EPA Substance Registry System: E-2-(2 4-DIFLUOROPHENYL)VINYLBORONIC AC&(736987-78-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 736987-78-3(Hazardous Substances Data)

Usage

General Description

E-2-(2,4-Difluorophenyl)vinylboronic acid, also known as 2,4-difluorostyrylboronic acid, is a chemical compound that belongs to the class of organoboron compounds. It is commonly used as a reagent in organic synthesis for the preparation of various important organic compounds, including pharmaceuticals and agrochemicals. E-2-(2 4-DIFLUOROPHENYL)VINYLBORONIC AC& has a vinyl group and a boronic acid group attached to a 2,4-difluorophenyl ring, making it a valuable building block in the development of new and diverse chemical entities. Its properties and structure make it a versatile and valuable tool in the field of organic chemistry and drug discovery.

InChI:InChI=1/C14H17BF2O2/c1-13(2)14(3,4)19-15(18-13)8-7-10-5-6-11(16)9-12(10)17/h5-9H,1-4H3/b8-7+

Upstream product

• 288101-48-4 2-(2,4-difluorophenyl)-4,4, 5,5-tetramethyl-1,3,2-dioxaborolane 
• 1105069-27-9 (E)-2-bromovinylboronic acid N-methyliminodiacetic ester 
• 73183-34-3 bis(pinacol)diborane 
• 302912-34-1 2,4-difluoroethynylbenzene 

Relevant articles and documents

Electrochemical Hydroboration of Alkynes

Herein we reported the electrochemical hydroboration of alkynes by using B2Pin2 as the boron source. This unprecedented reaction manifold was applied to a broad range of alkynes, giving the hydroboration products in good to excellent yields without the need of a metal catalyst or a hydride source. This transformation relied on the possible electrochemical oxidation of an in situ formed borate. This anodic oxidation performed in an undivided cell allowed the formation of a putative boryl radical, which reacted on the alkyne.

Chemoselective Boronic Ester Synthesis by Controlled Speciation

Control of boronic acid solution speciation is presented as a new strategy for the chemoselective synthesis of boronic esters. Manipulation of the solution equilibria within a cross-coupling milieu enables the formal homologation of aryl and alkenyl boron