7370-88-9

Basic information

• Product Name: N-ETHYLMETHACRYLAMIDE
• Synonyms: N-ETHYLMETHACRYLAMIDE
• CAS NO: 7370-88-9
• Molecular Formula: C₆H₁₁NO
• Molecular Weight: 113.16
• Product Categories: monomer
• Mol File: 7370-88-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 106℃/4mm
• Boiling Point: 233.7°C at 760 mmHg
• Flash Point: 125.6°C
• Appearance: /
• Density: 0.881g/cm³
• Vapor Pressure: 0.0551mmHg at 25°C
• Refractive Index: 1.428
• CAS DataBase Reference: N-ETHYLMETHACRYLAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-ETHYLMETHACRYLAMIDE(7370-88-9)
• EPA Substance Registry System: N-ETHYLMETHACRYLAMIDE(7370-88-9)

Safety Data

• Hazardous Substances Data: 7370-88-9(Hazardous Substances Data)

Usage

General Description

N-Ethylmethacrylamide is a chemical compound with the molecular formula C6H11NO2. It is a colorless liquid that is used in the production of polymers and as a monomer in the synthesis of various copolymers. N-Ethylmethacrylamide is primarily used in the manufacturing of hydrogels, which are materials with a high water content and are used in a wide range of applications including drug delivery, tissue engineering, and contact lenses. It is also used in the production of specialty coatings, adhesives, and textiles. N-Ethylmethacrylamide is considered to be relatively low in toxicity, but exposure to high concentrations can cause irritation to the skin, eyes, and respiratory system.

InChI:InChI=1/C6H11NO/c1-4-7-6(8)5(2)3/h2,4H2,1,3H3,(H,7,8)

Upstream product

• 79-41-4 poly(methacrylic acid) 
• 75-04-7 ethylamine 
• 80-62-6 methacrylic acid methyl ester 
• 920-46-7 Methacryloyl chloride 
• 75-03-6 ethyl iodide 
• 79-39-0 Methacrylamide 

Downstream Products

• 111875-31-1 N-benzoylformyl-N-ethylmethacrylamide 
• 111875-41-3 3-ethyl-1-methyl-5-phenyl-6-oxa-3-azabicyclo<3.1.1>heptane-2,4-dione 
• 1155870-78-2 tert-Butyl (6R)-6-({5-[(1E)-3-(ethylamino)-2-methyl-3-oxoprop-1-en-1-yl]-6-phenylfuro[2,3-d]pyrimidin-4-yl}oxy)heptanoate 

Relevant articles and documents

Effect of Transition Metals on Chemodivergent Cross-Coupling of Acrylamides with Vinyl Acetate via C-H Activation

A novel chemodivergent cross-coupling of acrylamides and vinyl acetates has been realized via metal-catalyzed vinylic C-H activation. The selective olefinic C-H vinylation and alkenylation reaction was examined with a variety of differently functionalized acrylamides. The reaction efficiently generates a range of highly synthetically valuable butadienes with good functional group tolerance in good to moderate yields. A possible catalytic reaction mechanism involving the chelation-assisted olefinic C-H activation via an acetate-assisted deprotonation pathway is proposed.

N-alkylation of methacrylamide with alkyl halides

N-Alkylation of methacrylamide with ethyl bromide, ethyl iodide, and allyl bromide in acetonitrile in the presence of alkalis yields N- and N,N-substituted methacrylamides. The effect of temperature, reactant ratio, nature of the alkyl halide, and water content on the reaction course was studied.