73713-67-4

Basic information

• Product Name: p-(m-Nitrobenzylidene)aminobenzoic acid ethyl ester
• Synonyms: p-(m-Nitrobenzylidene)aminobenzoic acid ethyl ester
• CAS NO: 73713-67-4
• Molecular Formula: C₁₆H₁₄N₂O₄
• Molecular Weight: 298.2934
• Mol File: 73713-67-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 152 °C(Solv: ethanol (64-17-5))
• Boiling Point: 466.8°Cat760mmHg
• Flash Point: 236.1°C
• Appearance: /
• Density: 1.21g/cm³
• Vapor Pressure: 6.87E-09mmHg at 25°C
• Refractive Index: 1.58
• PKA: 1.76±0.50(Predicted)
• CAS DataBase Reference: p-(m-Nitrobenzylidene)aminobenzoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: p-(m-Nitrobenzylidene)aminobenzoic acid ethyl ester(73713-67-4)
• EPA Substance Registry System: p-(m-Nitrobenzylidene)aminobenzoic acid ethyl ester(73713-67-4)

Safety Data

• Hazardous Substances Data: 73713-67-4(Hazardous Substances Data)

Usage

Description

p-(m-Nitrobenzylidene)aminobenzoic acid ethyl ester is a chemical compound that is commonly used in organic synthesis and pharmaceutical research. It is an ethyl ester derivative of p-(m-Nitrobenzylidene)aminobenzoic acid, known for its potential application as a photosensitive material in photolithographic processes. p-(m-Nitrobenzylidene)aminobenzoic acid ethyl ester has been studied for its ability to undergo reversible photoisomerization, making it useful for creating photoresponsive materials. It has also been investigated as a potential ingredient in sunscreen formulations due to its UV-absorbing properties. Additionally, p-(m-Nitrobenzylidene)aminobenzoic acid ethyl ester has shown potential in the development of optical coatings, sensors, and other advanced materials.

Uses

Used in Photolithographic Processes:
p-(m-Nitrobenzylidene)aminobenzoic acid ethyl ester is used as a photosensitive material for creating photomasks and photoresists in photolithographic processes. Its reversible photoisomerization property allows for the development of photoresponsive materials, which can be used in the fabrication of microelectronic devices and other applications.
Used in Sunscreen Formulations:
p-(m-Nitrobenzylidene)aminobenzoic acid ethyl ester is used as an ingredient in sunscreen formulations for its UV-absorbing properties. This helps protect the skin from harmful ultraviolet radiation, reducing the risk of skin damage and skin cancer.
Used in Optical Coatings:
p-(m-Nitrobenzylidene)aminobenzoic acid ethyl ester is used as a component in the development of optical coatings. Its photosensitive properties enable the creation of coatings that can change their optical properties in response to light, which can be useful in various applications such as smart windows and optical devices.
Used in Sensor Development:
p-(m-Nitrobenzylidene)aminobenzoic acid ethyl ester is used in the development of sensors due to its ability to undergo reversible photoisomerization. This property allows for the creation of sensors that can detect and respond to changes in light intensity or other environmental factors.
Used in Advanced Materials:
p-(m-Nitrobenzylidene)aminobenzoic acid ethyl ester is used in the development of advanced materials with unique properties. Its photosensitive nature and potential for reversible photoisomerization make it a promising candidate for applications in areas such as nanotechnology, optoelectronics, and other cutting-edge fields.

InChI:InChI=1/C16H14N2O4/c1-2-22-16(19)13-6-8-14(9-7-13)17-11-12-4-3-5-15(10-12)18(20)21/h3-11H,2H2,1H3/b17-11+

Upstream product

• 99-61-6 3-nitro-benzaldehyde 
• 94-09-7 p-aminoethylbenzoate 

Downstream Products

• 1343453-34-8 4-hydroxy-3,3-dimethyl-2-(3-nitro-phenyl)-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid ethyl ester 
• 1343453-30-4 2-[3-(3-benzyl-ureido)-phenyl]-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 
• 1343453-54-2 3,3-dimethyl-2-{3-[(pyridine-3-carbonyl)-amino]-phenyl}-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 
• 1343453-56-4 3,3-dimethyl-2-{3-[(pyridine-2-carbonyl)-amino]-phenyl}-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 
• 1343453-58-6 3,3-dimethyl-2-{3-[(pyrazine-2-carbonyl)-amino]-phenyl}-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 
• 1343453-61-1 2-[3-(3-fluoro-benzoylamino)-phenyl]-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 
• 1343453-87-1 pyrazine-2-carboxylic acid [3-(6-methanesulfonylaminocarbonyl-3,3-dimethyl-1,2,3,4-tetrahydro-quinolin-2-yl)-phenyl]-amide 
• 1343453-98-4 2-{3-[3-(3-fluoro-phenyl)-ureido]-phenyl}-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 
• 1343454-04-5 2-[3-(1-carboxy-1-methyl-ethylamino)-phenyl]-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 
• 1343454-16-9 2-[3-(4-fluoro-benzoylamino)-phenyl]-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 
• 1343454-18-1 3,3-dimethyl-2-{3-[(morpholine-4-carbonyl)-amino]-phenyl}-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 
• 1343454-23-8 3,3-dimethyl-2-{3-[(piperidine-1-carbonyl)-amino]-phenyl}-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 
• 1343454-33-0 2-(3-(N,N-dimethylsulfamoylamino)phenyl)-3,3-dimethyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid 
• 1343454-40-9 3,3-dimethyl-2-{3-[(4-methyl-piperazine-1-carbonyl)-amino]-phenyl}-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 

Relevant articles and documents

Synthesis of novel β-amino ketones containing a p-aminobenzoic acid moiety and evaluation of their antidiabetic activities

The synthesis of two series of β-amino ketones containing a p-aminobenzoic acid moiety (TM-1 and TM-2) using a modified protocol of the Mannich reaction is reported. The molecular structures of a total of tweenty three new target compounds were characterized by 1H NMR, 13C NMR, ESI-MS and HR-MS. Subsequently, their antidiabetic activities were screened in vitro. The α-glucodase inhibition (α-GI) activity of compound 1e reached a remarkable level of 66.50%. The peroxisome proliferator-activated receptor (PPAR) relative activation activities of six compounds are above 80%, and in particular 2i displays an unprecedentedly high PPAR of 130.91%. The structure-activity relationships of the compounds were established. 2i is also subject to further in-depth investigation.

NOVEL 3,3-DIMETHYL TETRAHYDROQUINOLINE DERIVATIVES

A compound of formula (I) as well as pharmaceutically acceptable salt thereof, wherein R1 to R5 have the significance given in claim 1, can be used as a medicament.

Synthesis of aminophosphonates with a primary amino group

Mono- and dinitro-substituted aromatic Shiff bases were reacted with diisopropyl hydrogen phosphite in the presence of the boron trifluoride-ether complex to obtain the corresponding α-aminophosphonates. Reduction of the nitro groups in the resulting phos