73721-76-3 Usage
Description
5-BROMO-2-BUTYRAMIDOBENZOIC ACID is a chemical compound characterized by its molecular formula C11H13BrNO3. It presents as a white to off-white crystalline powder and is primarily utilized as an intermediate in the synthesis of pharmaceuticals and other organic compounds. Additionally, it serves as a reagent in chemical research and organic synthesis. Due to its potential health hazards, it is crucial to handle, store, and use this chemical with caution, ensuring proper safety procedures are followed in a well-ventilated environment, and keeping it away from ignition sources, heat, and oxidizing agents.
Uses
Used in Pharmaceutical Industry:
5-BROMO-2-BUTYRAMIDOBENZOIC ACID is used as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical structure allows it to be a versatile building block in medicinal chemistry.
Used in Chemical Research and Organic Synthesis:
As a reagent, 5-BROMO-2-BUTYRAMIDOBENZOIC ACID is employed in chemical research and organic synthesis for the development of novel compounds and materials. Its properties make it suitable for use in a wide range of chemical reactions and processes, aiding in the advancement of scientific knowledge and the creation of new chemical entities.
Check Digit Verification of cas no
The CAS Registry Mumber 73721-76-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,7,2 and 1 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 73721-76:
(7*7)+(6*3)+(5*7)+(4*2)+(3*1)+(2*7)+(1*6)=133
133 % 10 = 3
So 73721-76-3 is a valid CAS Registry Number.
73721-76-3Relevant articles and documents
Lead derivatization of ethyl 6-bromo-2-((dimethylamino)methyl)-5-hydroxy-1-phenyl-1H-indole-3-carboxylate and 5-bromo-2-(thiophene-2-carboxamido) benzoic acid as FabG inhibitors targeting ESKAPE pathogens
Varakala, Saiprasad Dasugari,Reshma, Rudraraju Srilakshmi,Schnell, Robert,Dharmarajan, Sriram
supporting information, (2021/11/26)
Our previous studies on FabG have identified two compounds 5-bromo-2-(thiophene-2-carboxamido) benzoic acid (A) and ethyl 6-bromo-2-((dimethylamino)methyl)-5-hydroxy-1-phenyl-1H-indole-3-carboxylate(B) as best hits with allosteric mode of inhibition. FabG is an integral part of bacterial fatty acid biosynthetic system FAS II shown to be an essential gene in most ESKAPE Pathogens. The current work is focussed on lead expansion of these two hit molecules which ended up with forty-three analogues (twenty-nine analogues from lead compound A and fourteen compounds from lead compound B). The enzyme inhibition studies revealed that compound 15 (effective against EcFabG, AbFabG, StFabG, MtFabG1) and 19 (inhibiting EcFabG and StFabG) had potency of broad-spectrum inhibition on FabG panel.
