73726-09-7

Basic information

• Product Name: 6-Phthalazinecarboxylic acid, 3-(2-chlorophenyl)-3,4-dihydro-1-(hydroxymethyl)-5,7-dimethyl-4-oxo-, ethyl ester
• CAS NO: 73726-09-7
• Molecular Formula: C20H19ClN2O4
• Molecular Weight: 386.835
• Mol File: 73726-09-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-Phthalazinecarboxylic acid, 3-(2-chlorophenyl)-3,4-dihydro-1-(hydroxymethyl)-5,7-dimethyl-4-oxo-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Phthalazinecarboxylic acid, 3-(2-chlorophenyl)-3,4-dihydro-1-(hydroxymethyl)-5,7-dimethyl-4-oxo-, ethyl ester(73726-09-7)
• EPA Substance Registry System: 6-Phthalazinecarboxylic acid, 3-(2-chlorophenyl)-3,4-dihydro-1-(hydroxymethyl)-5,7-dimethyl-4-oxo-, ethyl ester(73726-09-7)

Safety Data

• Hazardous Substances Data: 73726-09-7(Hazardous Substances Data)

Upstream product

• 56611-61-1 6-ethoxycarbonyl-5,7-dimethyl-3-hydroxy-3-methylphthalide 
• 41052-75-9 o-chlorophenylhydrazine hydrochloride 

Relevant articles and documents

Synthesis and inhibitory effects on platelet aggregation of phthalazinone derivatives

7-Ethoxycarbonyl-4-hydroxymethyl-6,8-dimethyl-2-phenyl-1(2H)-phthalazinon e 7a and its derivatives having various substituents on the benzene ring at the 2 position were prepared and their inhibitory activities on platelet aggregation were assayed. The parent compound and those having an ortho substituent such as fluorine, chlorine atom or a methyl group showed the most potent inhibitory activity. Their inhibitory mechanism on platelet aggregation was assumed to be inhibition of cyclooxygenase, resulting in prevention of prostaglandin synthesis.