73763-45-8

Basic information

• Product Name: L-Threonine, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanyl]-, methyl ester
• CAS NO: 73763-45-8
• Molecular Formula: C19H28N2O6
• Molecular Weight: 380.441
• Mol File: 73763-45-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: L-Threonine, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Threonine, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanyl]-, methyl ester(73763-45-8)
• EPA Substance Registry System: L-Threonine, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanyl]-, methyl ester(73763-45-8)

Safety Data

• Hazardous Substances Data: 73763-45-8(Hazardous Substances Data)

Upstream product

• 3373-59-9 L-threonine methyl ester 
• 18942-49-9 Boc-D-Phe-OH 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 39994-75-7 L-threonine methyl ester hydrochloride 

Downstream Products

• 118140-26-4 Boc-L-Phe-Z-ΔAbu-OMe 
• 73763-61-8 Phe-Thr-OMe 
• 1257861-35-0 (S)-methyl 2-(1-((tert-butoxycarbonyl)amino)-2-phenylethyl)-5-methyloxazole-4-carboxylate 
• 126188-49-6 (1S,2S)-N-<(2-Hydroxy-2-phenyl)-1-methyl-ethyl>-acetamid 
• 87363-79-9 Boc-(L)-Ala-Δbut-OMe 
• 530151-17-8 (E)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-but-2-enoic acid methyl ester 

Relevant articles and documents

Marine natural occurring 2,5-diketopiperazines: Isolation, synthesis and optical properties

Seven 2,5-diketopiperazines (DKPs) were isolated from the Fijian marine sponge Acanthella cavernosa. NMR and circular dichroism (CD) comparison with synthetic L-L DKPs allowed us to determine unambiguously the L-L absolute configuration of the natural DKPs. This work initiated the setting up of an optical properties database of natural DKPs, including specific rotation and CD.

Total synthesis of wewakazole B

Wewakazole B is a novel cyclodecapeptide with highly potent cytotoxic activity isolated from a sample of M. producens collected from the Red Sea. It contains nine common and three modified amino acid residues. The first total synthesis of Wewakazole B was successfully achieved on a gram scale, unambiguously confirming its structure. Notable features include the careful choice of amino acid-protecting groups and the construction of three different substituted oxazoles present in this natural product.