73806-22-1Relevant articles and documents
Solid sodium hydroxide - THF, convenient system for synthesis esters of glycidic acids by darzens condensation
Gadaj,Kowalkowska,Jonczyk
, p. 577 - 584 (2008/09/19)
Isopropyl- and tert-butylchloroacetate react with carbonyl compounds in the presence of powdered sodium hydroxide in THF, without a catalyst, giving substituted glycidates. The process is applied for preparation of glycidates from ketones, hitherto unavailable by phase-transfer catalyzed Darzens condensation.