73810-75-0

Basic information

• Product Name: 6H-Pyrazolo[3,4-b]pyridin-6-one, 1,2-dihydro-2,4-dimethyl-
• CAS NO: 73810-75-0
• Molecular Formula: C8H9N3O
• Molecular Weight: 163.179
• Mol File: 73810-75-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6H-Pyrazolo[3,4-b]pyridin-6-one, 1,2-dihydro-2,4-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 6H-Pyrazolo[3,4-b]pyridin-6-one, 1,2-dihydro-2,4-dimethyl-(73810-75-0)
• EPA Substance Registry System: 6H-Pyrazolo[3,4-b]pyridin-6-one, 1,2-dihydro-2,4-dimethyl-(73810-75-0)

Safety Data

• Hazardous Substances Data: 73810-75-0(Hazardous Substances Data)

Upstream product

• 91027-92-8 N-(1-methyl-3-pyrazolyl)-acetoacetamide 

Relevant articles and documents

STUDIES IN THE FIELD OF NITROGEN HETEROCYCLIC COMPOUNDS. PART X. SYNTHESIS AND NEW RING TRANSFORMATION OF SOME FUSED PYRAZOLE SYSTEMS

Condensation of 3-amino-1-methylpyrazole (7) with ethyl acetoacetate (1) in ethanol leads to formation of aminocrotonate 8, whereas the reaction in Dowtherm A above 200 deg C gives acetoacetamide (9).Ring closure of 8 in polyphosphoric acid (PPA) or ethanolic hydrochloride gives pyrazolopyrimidine (10).However, in Dowtherm A besides compound 10, the pyrazolopyridine (11) is also formed.Heating of 10 in Dowtherm A at 220-240 deg C causes ring transformation into 11.In acetic acid, compound 8 undergoes rearrangement to acetoacetamide 9 prior to cyclization into pyrazolopyridine (12).The structures of the compounds obtained were deduced from their IR, MS, 1H NMR and 13C NMR spectra.Pathways of the reactions presented are also discussed.