73818-40-3

Basic information

• Product Name: 1-(1-Pyrazolyl)-2-(triphenylphosphoranyliden)ethanon
• CAS NO: 73818-40-3
• Molecular Weight: 370.39
• Mol File: 73818-40-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(1-Pyrazolyl)-2-(triphenylphosphoranyliden)ethanon(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-Pyrazolyl)-2-(triphenylphosphoranyliden)ethanon(73818-40-3)
• EPA Substance Registry System: 1-(1-Pyrazolyl)-2-(triphenylphosphoranyliden)ethanon(73818-40-3)

Safety Data

• Hazardous Substances Data: 73818-40-3(Hazardous Substances Data)

Upstream product

• 288-13-1 NH-pyrazole 
• 73818-55-0 Bestmann ylide 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 

Relevant articles and documents

Catalyst-Enabled Site-Divergent Stereoselective Michael Reactions: Overriding Intrinsic Reactivity of Enynyl Carbonyl Acceptors

A site-divergent stereoselective Michael reaction system is developed based on the identification of two distinct catalysts. Cinchonidine-derived thiourea catalyzes the 1,4-addition of prochiral azlactone enolates to enynyl N-acyl pyrazoles in a highly diastereo- and enantioselective manner to give stereochemically defined alkynes, while P-spiro chiral triaminoiminophosphorane catalytically controls the stereoselective 1,6-addition and the consecutive γ-protonation of the vinylogous enolate intermediate to afford Z,E-configured conjugated dienes. This 1,6-adduct serves as a valuable precursor for the synthesis of a 2-amino-2-deoxy sugar.