73859-65-1Relevant articles and documents
Expeditious and Convenient Synthesis of Polycyclic Difluoroboron Complexes of 2-Oxoindoline-3-carboxamides by Tandem Reaction
Mo, Shanyan,Xu, Chuangchuang,Xu, Jiaxi
, p. 1767 - 1777 (2016/06/09)
N-Aryl-2-cyanodiazoacetamides produce polycyclic difluoroboron 2-oxoindoline-3-carboxamide complexes (up to pentacyclic conjugative and fused systems) directly and expeditiously in the presence of boron trifluoride etherate. The boron trifluoride serves as both a catalyst and reactant in the tandem reaction. The tandem reaction includes the carbene aromatic C-H insertion, hydrolysis of the cyano group into an amide group, and boronation of the two amide carbonyl groups. The synthetic method features the advantages of wide substrate scope and excellent chemoselectivity.