73871-00-8

Basic information

• Product Name: Z-D-Phe-L-Pro-L-Val-OMe
• Synonyms: Z-D-Phe-L-Pro-L-Val-OMe
• CAS NO: 73871-00-8
• Molecular Weight: 509.602
• Mol File: 73871-00-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Z-D-Phe-L-Pro-L-Val-OMe(CAS DataBase Reference)
• NIST Chemistry Reference: Z-D-Phe-L-Pro-L-Val-OMe(73871-00-8)
• EPA Substance Registry System: Z-D-Phe-L-Pro-L-Val-OMe(73871-00-8)

Safety Data

• Hazardous Substances Data: 73871-00-8(Hazardous Substances Data)

Upstream product

• 6306-52-1 L-valine methylester hydrochloride 
• 17460-56-9 N-[[(Phenylmethoxy)-carbonyl]-D-phenylalanyl]-L-proline 
• 2448-45-5 Cbz-D-Phe 
• 2874-20-6 benzyloxycarbonyl-L-prolin-L-valin methyl ester 

Relevant articles and documents

Tandem deprotection/coupling for peptide synthesis in water at room temperature

A tandem deprotection/coupling sequence is reported for solution-phase peptide synthesis in water under micellar catalysis conditions using the designer surfactant TPGS-750-M. Cbz deprotection followed by peptide coupling in the presence of COMU and 2,6-lutidine afforded polypeptides containing up to 10 amino acid residues. A broad scope characterizes this new technology. No epimerization has been detected. The associated E Factors, as a measure of "greenness" and known to be extremely high for peptide couplings, have been reduced to less than 10 due to the step-economy and minimal amounts of organic solvent needed for product extraction.