73894-40-3

Basic information

• Product Name: (+/-)-7-bromo-8-methoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
• Synonyms: (+/-)-7-bromo-8-methoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
• CAS NO: 73894-40-3
• Molecular Weight: 332.24
• Mol File: 73894-40-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (+/-)-7-bromo-8-methoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-7-bromo-8-methoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine(73894-40-3)
• EPA Substance Registry System: (+/-)-7-bromo-8-methoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine(73894-40-3)

Safety Data

• Hazardous Substances Data: 73894-40-3(Hazardous Substances Data)

Upstream product

• 62717-61-7 8-methoxy1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine 
• 55-81-2 4-Methoxyphenethylamine 
• 65458-23-3 α-<methyl>benzyl alcohol 
• 96-09-3 styrene oxide 
• 159465-27-7 3-Bromo-4-methoxyphenethylamine 
• 772-59-8 (3-bromo-4-methoxyphenyl)-acetonitrile 
• 171285-31-7 2-amino>-1-phenylethanol 

Downstream Products

• 179694-25-8 (E)-1-(7-Bromo-8-methoxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-3-(4-dimethylamino-phenyl)-propenone 
• 137464-90-5 3-allyl-7-bromo-8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine 
• 73894-47-0 2,2,2-Trifluoro-1-(8-methoxy-1-phenyl-7-trifluoromethyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-ethanone 
• 73894-52-7 2,2,2-Trifluoro-1-(8-hydroxy-1-phenyl-7-trifluoromethyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-ethanone 
• 171285-38-4 [4-(7-Bromo-8-methoxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-butyl]-dimethyl-amine 
• 179694-27-0 {4-[(E)-3-(7-Bromo-8-methoxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-propenyl]-phenyl}-dimethyl-amine 
• 171285-34-0 (+/-)-7-bromo-8-methoxy-3-<4-(N,N-dimethylamino)butanoyl>-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine 
• 73894-42-5 1-(7-Bromo-8-methoxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-2,2,2-trifluoro-ethanone 
• 113081-32-6 7-bromo-8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide 

Relevant articles and documents

Structural manipulation on the catecholic fragment of dopamine D 1 receptor agonist 1-phenyl-N-methyl-benzazepines

A series of new benzazepines with modification on the catecholic fragment were designed. The 8-hydroxyl group, other than the 7-hydroxyl was confirmed crucial to the interaction with the dopamine D1 receptor. Subsequent replacement of the 7-hyd

(±)-3-Allyl-7-halo-8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3- benzazepines as selective high affinity D1 dopamine receptor antagonists: Synthesis and structure-activity relationship

Substituted 1-phenyl-3-benzazepines form a class of compounds possessing potent and selective affinity for the D1 DA receptor. 7,8-Dihydroxy-1-phenyl- 2,3,4,5-tetrahydro-1H-3-benzazepine (SKF 38393) and its 6-halo analogues are potent and selective D1 rec