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73944-54-4

73944-54-4

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73944-54-4 Usage

Type of Compound

Nitrosourea

Function

Chemotherapy medication

Mechanism of Action

Potent alkylating agent that inhibits DNA synthesis and causes DNA damage in cancer cells, leading to cell death

Cancer Treatments

Brain tumors, Hodgkin's lymphoma, and melanoma

Administration

Oral

Absorption

Well-absorbed in the gastrointestinal tract

Half-life

Long, allowing for once-monthly dosing

Side Effects

Myelosuppression, pulmonary toxicity, and gastrointestinal disturbances

Monitoring and Management

Proper monitoring and management of side effects are important during treatment with lomustine

Check Digit Verification of cas no

The CAS Registry Mumber 73944-54-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,9,4 and 4 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 73944-54:
(7*7)+(6*3)+(5*9)+(4*4)+(3*4)+(2*5)+(1*4)=154
154 % 10 = 4
So 73944-54-4 is a valid CAS Registry Number.

73944-54-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[2-(2-chloroethylsulfinyl)ethyl]-3-cyclohexyl-1-nitrosourea

1.2 Other means of identification

Product number -
Other names 1-chloro-2-trimethylsilanyloxy-ethane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:73944-54-4 SDS

73944-54-4Relevant articles and documents

Novel Antitumor Nitrosoureas and Related Compounds and Their Reactions with DNA

Lown, J. William,Joshua, Alummoottil V.,McLaughlin, Larry W.

, p. 798 - 805 (2007/10/02)

A number of nitrosoureas have been synthesized in order to examine those structural features which lead to optimum interstrand DNA cross-linking as this property may relate to their cytotoxicity and antitumor effects.The compounds include 2-chloroethyl tr

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