740-57-8

Basic information

• Product Name: H-PHE-BETANA
• Synonyms: H-Phe-bNA;(2S)-2-amino-N-(2-naphthyl)-3-phenyl-propionamide;(2S)-2-amino-N-naphthalen-2-yl-3-phenylpropanamide;(2S)-2-azanyl-N-naphthalen-2-yl-3-phenyl-propanamide;H-Phe-βNA;N-2-naphthylphenylalaninamide;L-Phe-bNA;L-Phenylalanine b-naphthylamide≥ 99% (TLC)
• CAS NO: 740-57-8
• Molecular Formula: C₁₉H₁₈N₂O
• Molecular Weight: 290.36
• EINECS: 212-009-9
• Product Categories: Amino Acids;I - Z;Modified Amino Acids
• Mol File: 740-57-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 129-131 °C(lit.)
• Boiling Point: 550.4 °C at 760 mmHg
• Flash Point: 286.7 °C
• Appearance: /
• Density: 1.22 g/cm³
• Vapor Pressure: 3.66E-12mmHg at 25°C
• Refractive Index: 1.69
• Storage Temp.: −20°C
• PKA: 14.09±0.30(Predicted)
• CAS DataBase Reference: H-PHE-BETANA(CAS DataBase Reference)
• NIST Chemistry Reference: H-PHE-BETANA(740-57-8)
• EPA Substance Registry System: H-PHE-BETANA(740-57-8)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-40
• Safety Statements: 22-36
• WGK Germany: 3
• Hazardous Substances Data: 740-57-8(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Definition

ChEBI: An L-phenylalanine derivative that is the amide obtained by formal condensation of the carboxy group of L-phenylalanine with the amino group of 2-naphthylamine.

InChI:InChI=1/C19H18N2O/c20-18(12-14-6-2-1-3-7-14)19(22)21-17-11-10-15-8-4-5-9-16(15)13-17/h1-11,13,18H,12,20H2,(H,21,22)/t18-/m0/s1

Upstream product

• 5249-47-8 N-Formyl-L-phenylalanin-<2>naphthylamid 
• 16876-73-6 N-Benzyloxycarbonyl-L-phenylalanin-<2>naphthylamid 
• 109057-27-4 tert-butyloxycarbonyl-L-phenylalanine 2-naphthylamide 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 91-59-8 naphthalen-2-ylamine 
• 13200-85-6 N-formyl-L-phenylalanine 
• 1161-13-3 N-Cbz-L-Phe 

Relevant articles and documents

Addressing the stability of C-capped dipeptide efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa

Synthetic optimization of a biologically labile class of dipeptides that function as efflux pump inhibitors to potentiate the antibacterial agent levofloxacin in Pseudomonas aeruginosa has led to the discovery of a related series of compounds that are completely stable in a variety of biological matrices. Other than the stability profile, the in vitro profile of the new series is essentially identical to that observed with the original one. A prototypical compound from the new series demonstrates potentiation in an in vivo model of infection.