7400-24-0 Usage
Therapeutic Potential
Investigated for cancer treatment
Mechanism of Action
Selective inhibitor of the insulin-like growth factor-1 receptor (IGF-1R)
Biological Role of IGF-1R
Involved in cell growth and survival
Effects
Inhibits growth and proliferation of cancer cells
Investigated for enhancing efficacy of chemotherapy and radiation therapy
Research Status
Ongoing for understanding its therapeutic potential in cancer treatment
Check Digit Verification of cas no
The CAS Registry Mumber 7400-24-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,0 and 0 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7400-24:
(6*7)+(5*4)+(4*0)+(3*0)+(2*2)+(1*4)=70
70 % 10 = 0
So 7400-24-0 is a valid CAS Registry Number.
7400-24-0Relevant articles and documents
Alkylpurines as immunopotentiating agents. Synthesis and antiviral activity of certain alkylguanines.
Michael,Cottam,Smee,Robins,Kini
, p. 3431 - 3436 (2007/10/02)
Several simple 8-substituted 9-alkyl- and 7,8-disubstituted 9-alkylguanine derivatives were synthesized as potential antiviral agents. These were tested for antiviral protection against a lethal Semliki Forest virus (SFV) infection in mice, and their anti