74003-18-2 Usage
Description
Ozagrel Hydrochloride is a pharmaceutical compound that functions as a selective thromboxane A2 synthase inhibitor. It is known for its ability to alleviate liver injury induced by acetaminophen overdose in mice, making it a potential candidate for the treatment of liver-related conditions.
Uses
Used in Pharmaceutical Industry:
Ozagrel Hydrochloride is used as a therapeutic agent for the treatment of liver injury. Its application is based on its ability to inhibit thromboxane A2 synthase, which plays a role in the development of liver injury caused by acetaminophen overdose in mice. This makes it a promising compound for the development of treatments aimed at reducing liver damage and improving patient outcomes in cases of acetaminophen-induced liver injury.
Biological Activity
Potent and selective inhibitor of thromboxane (TXA 2 ) synthetase (IC 50 = 4 nM). Does not inhibit prostacyclin (PGI 2 ) synthetase, cyclooxygenase or PGE 2 isomerase (IC 50 > 1 mM). Inhibits platelet aggregation in vitro and arachidonate-induced arterial contraction in vivo .
Check Digit Verification of cas no
The CAS Registry Mumber 74003-18-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,0,0 and 3 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 74003-18:
(7*7)+(6*4)+(5*0)+(4*0)+(3*3)+(2*1)+(1*8)=92
92 % 10 = 2
So 74003-18-2 is a valid CAS Registry Number.
