740039-33-2

Basic information

• Product Name: Proline, 5-imino-1-methyl-, methyl ester (9CI)
• Synonyms: Proline, 5-imino-1-methyl-, methyl ester (9CI)
• CAS NO: 740039-33-2
• Molecular Formula: C7H12N2O2
• Molecular Weight: 156.18238
• Product Categories: CARBOXYLICESTER;AMINETERTIARY;GLYCINESCAFFOLD
• Mol File: 740039-33-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Proline, 5-imino-1-methyl-, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Proline, 5-imino-1-methyl-, methyl ester (9CI)(740039-33-2)
• EPA Substance Registry System: Proline, 5-imino-1-methyl-, methyl ester (9CI)(740039-33-2)

Safety Data

• Hazardous Substances Data: 740039-33-2(Hazardous Substances Data)

Upstream product

• 591225-53-5 tert-butyl (2S)-1-methyl-5-oxopyrrolidine-2-carboxylate 
• 915127-35-4 (-)-(5S)-2-imino-1-methylpyrrolidine-5-carboxylic acid 
• 67-56-1 methanol 
• 35418-16-7 L-t-butyl pyroglutamate 
• 914805-66-6 (+)-(S)-tert-butyl 2-(methoxysulfonylimino)-1-methylpyrrolidine-5-carboxylate 

Relevant articles and documents

Isolation and synthesis of (-)-(5S)-2-Imino-1-methylpyrrolidine-5- carboxylic acid from cliona tenuis: Structure revision of pyrostatins

(-)-(5S)-2-Imino-1-methylpyrrolidine-5-carboxylic acid (1), previously reported as the N-acetyl-β-D-glucosaminidase inhibitor pyrostatin B, has been isolated from the organic extracts of the burrowing sponge Cliona tenuis. The structure of 1, including its absolute stereochemistry, was characterized from its spectral data and chemical transformations and confirmed by total synthesis. The synthesis of 1 reveals that the structure of pyrostatin B has been incorrectly assigned. Comparison of NMR spectral data strongly suggests that pyrostatins A and B are identical to 5-hydroxyectoine and ectoine, respectively.