740051-77-8Relevant articles and documents
THE HOFFMAN-LIKE FRAGMENTATION INDUCED BY N-ACYLATION OF 1-METHYL-1-AZA-4-CYCLANONES AND ITS USE IN THE SYNTHESIS OF 2-AZA-HYDRINDANONES AND 2-AZA-DECALONES
Levy, Jean,Laronze, Jean-Yves,Sapi, Janos
, p. 3303 - 3306 (2007/10/02)
The N-methyl-piperidone 4a was fragmented to the vinylketonic acrylamide 9a by successive treatment with acryloyl chloride and Huenig's base.The 2-azahydrindandione 13a resulted from the cyclization of 9a in the form of its enol dimethylterbutyl ether.N-methyl-azepinone 4b was transformed in a similar way to the two epimeric 2-azadecalindiones 13b + 14b in four steps only.