74010-51-8Relevant articles and documents
The Role of the Amino Protecting Group during Parahydrogenation of Protected Dehydroamino Acids
Cerutti, Erika,Viale, Alessandra,Nervi, Carlo,Gobetto, Roberto,Aime, Silvio
, p. 11271 - 11279 (2015/12/01)
A series of dehydroamino acids endowed with different protective groups at the amino and carboxylate moieties and with different substituents at the double bond have been reacted with parahydrogen. The observed ParaHydrogen Induced Polarization (PHIP) effects in the 1H NMR spectra are strongly dependent on the amino protecting group. DFT calculations allowed us to establish a relationship between the structures of the reaction intermediates (whose energies depend on the amido substitution) and the observed PHIP patterns.
Synthesis of the Antibiotic A 32390 A and Several Structural Variants
Wuest, Hans-Heiner,Bardenhagen, Juergen,Schoellkopf, Ulrich
, p. 1825 - 1837 (2007/10/02)
The title compound 4(= 13a) was synthesized via its tetra-O-formyl derivative 12a starting with the N-formyldehydrovaline 5a.Analogously, the structural variants 12b-d and 15a,c, and d were prepared which have different "end groups" at the double bond and