7402-30-4

Basic information

• Product Name: diethyl (3,4,5-trimethoxybenzyl)propanedioate
• CAS NO: 7402-30-4
• Molecular Formula: C₁₇H₂₄O₇
• Molecular Weight: 340.3683
• Mol File: 7402-30-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 418.1°C at 760 mmHg
• Flash Point: 180.8°C
• Density: 1.132g/cm³
• Vapor Pressure: 3.37E-07mmHg at 25°C
• Refractive Index: 1.491
• CAS DataBase Reference: diethyl (3,4,5-trimethoxybenzyl)propanedioate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl (3,4,5-trimethoxybenzyl)propanedioate(7402-30-4)
• EPA Substance Registry System: diethyl (3,4,5-trimethoxybenzyl)propanedioate(7402-30-4)

Safety Data

• Hazardous Substances Data: 7402-30-4(Hazardous Substances Data)

Upstream product

• 51444-50-9 diethyl 2-(3,4,5-trimethoxybenzylidene)malonate 
• 105-53-3 diethyl malonate 
• 3840-30-0 5-(chloromethyl)-1,2,3-trimethoxybenzene 
• 996-82-7 sodium diethylmalonate 
• 61040-77-5 trimethyl(3,4,5-trimethoxybenzyloxy)silane 
• 530-56-3 syringic alcohol 
• 3840-31-1 (3,4,5-trimethoxyphenyl)methanol 
• 36974-47-7 3,4,5-trimethoxy-N-phenyl-benzimidoyl chloride 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 1916-07-0 3,4,5-trimethoxybenzoic acid methyl ester 

Downstream Products

• 25173-72-2 3-(3,4,5-trimethoxyphenyl)propanoic acid 
• 97025-55-3 (3,4,5-trimethoxy-benzyl)-malonic acid 
• 152961-71-2 2-<(3,4,5-Trimethoxyphenyl)methyl>propane-1,3-diol 
• 104197-33-3 3,3-Bis-ethoxycarbonyl-4-(3,4,5-trimethoxy-phenyl)-butyric acid methyl ester 
• 154317-98-3 monoethyl 3,4,5-trimethoxybenzylmalonate 
• 205505-53-9 2-(3,4,5-Trimethoxy-benzyl)-acrylic acid ethyl ester 
• 205505-74-4 (S)-2,2-Dimethyl-4-(3,4,5-trimethoxy-benzyl)-[1,3]dioxolane-4-carbaldehyde 
• 205505-84-6 (S)-2-Hydroxy-2-hydroxymethyl-1-(2-hydroxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propan-1-one 
• 205505-70-0 (S)-2,2-Dimethyl-4-(3,4,5-trimethoxy-benzyl)-[1,3]dioxolane-4-carboxylic acid ethyl ester 
• 205505-80-2 [(S)-2,2-Dimethyl-4-(3,4,5-trimethoxy-benzyl)-[1,3]dioxolan-4-yl]-[2-(2-methoxy-ethoxymethoxy)-phenyl]-methanone 
• 205505-63-1 (S)-2-Hydroxy-2-hydroxymethyl-3-(3,4,5-trimethoxy-phenyl)-propionic acid ethyl ester 
• 152961-91-6 (R)-3-Cyano-2-<(3,4,5-trimethoxyphenyl)methyl>propyl acetate 
• 152961-85-8 (S)-3-<(p-Tolylsulfonyl)oxy>-2-<(3,4,5-trimethoxyphenyl)methyl>propyl acetate 
• 104197-34-4 3,3-Bis-ethoxycarbonyl-4-(3,4,5-trimethoxy-phenyl)-butyric acid 

Relevant articles and documents

Synthesis and activity evaluation of the cyclic dipeptides arylidene N-alkoxydiketopiperazines

A series of arylidene N-alkoxydiketopiperazines was designed and stereoselectively synthesized via oxime-ether formation and intramolecular acylation. Possible cyclization and acid-catalyzed rearrangement-fragmentation mechanisms were discussed. The crystal structure of the novel diketopiperazine further confirmed the rearrangement mechanism. Most compounds exhibited antitumor activity. Several compounds were more potent against caspase-3. Specifically, compounds 6e, 6g, and 6f inhibited caspase-3 at IC50values lying within the low micromolar range and demonstrated good selectivity. The binding modes of alkoxydiketopiperazines in the active center of caspase-3 were also discussed based on the molecular docking results.

An efficient enantioselective total synthesis of antitumor lignans: Synthesis of enantiomerically pure 4-hydroxyalkanenitriles via an enzymatic reaction

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