74029-45-1

Basic information

• Product Name: 4-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-benzaldehyde
• Synonyms: 4-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-benzaldehyde
• CAS NO: 74029-45-1
• Molecular Weight: 203.241
• Mol File: 74029-45-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-benzaldehyde(74029-45-1)
• EPA Substance Registry System: 4-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-benzaldehyde(74029-45-1)

Safety Data

• Hazardous Substances Data: 74029-45-1(Hazardous Substances Data)

Upstream product

• 109-72-8 n-butyllithium 
• 32664-14-5 2-(4-bromophenyl)-4,4-dimethyl-2-oxazoline 
• 74029-48-4 (4-(4,5-dihydro-4,4-dimethyloxazol-2-yl)phenyl)methanol 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 356072-65-6 1-[4-(4,4-Dimethyloxazolin-2-yl)phenyl]-1-(2-methoxyphenyl)methyl alcohol 
• 74029-49-5 2-(4-methoxymethyl-phenyl)-4,4-dimethyl-4,5-dihydro-oxazole 
• 74029-46-2 {2-[4-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-phenyl]-[1,3]dioxolan-2-yl}-phenyl-methanone 
• 74012-24-1 1-{2-[4-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-phenyl]-[1,3]dioxolan-2-yl}-2-methyl-propan-1-ol 
• 74012-23-0 2-[4-(2-allyl-[1,3]dioxolan-2-yl)-phenyl]-4,4-dimethyl-4,5-dihydro-oxazole 
• 74029-48-4 (4-(4,5-dihydro-4,4-dimethyloxazol-2-yl)phenyl)methanol 
• 74012-33-2 2-[4-(4c,6c-dimethyl-[1,3]dioxan-2r-yl)-phenyl]-4,4-dimethyl-4,5-dihydro-oxazole 
• 74012-33-2 2-[4-(4r,6t-dimethyl-[1,3]dioxan-2-yl)-phenyl]-4,4-dimethyl-4,5-dihydro-oxazole 
• 74012-19-4 2-(4-[1,3]dioxan-2-yl-phenyl)-4,4-dimethyl-4,5-dihydro-oxazole 
• 143976-72-1 4,4-dimethyl-2-[4-(trans-5-phenyl-[1,3]dioxan-2-yl)-phenyl]-4,5-dihydro-oxazole 
• 74012-20-7 4,4-dimethyl-2-[4-(5-phenyl-[1,3]dioxan-2-yl)-phenyl]-4,5-dihydro-oxazole 
• 74012-32-1 4,4-dimethyl-2-[4-(cis-4-methyl-[1,3]dioxan-2-yl)-phenyl]-4,5-dihydro-oxazole 
• 74012-35-4 4,4-dimethyl-2-[4-(4,4,6c-trimethyl-[1,3]dioxan-2r-yl)-phenyl]-4,5-dihydro-oxazole 
• 74012-17-2 2-(4-dimethoxymethyl-phenyl)-4,4-dimethyl-4,5-dihydro-oxazole 

Relevant articles and documents

Anti-inflammatory piperazinyl-benzyl-tetrazole derivatives and intermediates thereof

This invention relates to tetrazoles and their pharmaceutically acceptable salts which are selective agonists for the delta opioid receptor, particularly useful in the treatment of inflammatory diseases such as arthritis, psoriasis, asthma, inflammatory bowel disease, disorders or respiratory function, gastrointestinal disorders such as functional bowel disease and functional GI disorders, of formula (I) wherein R1is H, C2-C6alkanoyl, C1-C6alkyl, C2-C6alkenyl, C2-C6alkynyl, (C3-C7cycloalkyl)-(C1-C4alkyl), (C1-C4alkoxy)-(C1-C4alkyl), carboxy-(C1-C4alkyl), aryl-(C1-C4alkyl) or heteroaryl-(C1-C4alkyl); R2and R3are each independently H or C1-C4alkyl; R4is selected from (i) H, (ii) a group of the formula R6—(CH2)m—Z—(CH2)n—, where m is 0, 1, 2 or 3, n is 1, 2 or 3, Z is a direct link or O, and R6is —CO2H or —CO2(C1-C4alkyl), and (iii) a group of formula (a) where R7is H or C1-C4alkyl; and R5is hydroxy, C1-C4alkoxy or —NHSO2(C1-C4alkyl); with the proviso that when Z is O, m is 1, 2 or 3 and n is 2 or 3.