74047-22-6 Usage
General Description
2-Ethynyl-4-hydroxy-phenol is a chemical compound that belongs to the family of phenols. It is a derivative of phenol with an ethynyl group attached to the carbon at position 2. 2-ETHYNYL-4-HYDROXY-PHENOL is a pale yellow solid at room temperature and is commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. It is also used as a building block in the production of polymers and other industrial materials. Additionally, 2-ethynyl-4-hydroxy-phenol has been studied for its potential antioxidant and anti-inflammatory properties, making it a subject of interest in the field of medicinal and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 74047-22-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,0,4 and 7 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 74047-22:
(7*7)+(6*4)+(5*0)+(4*4)+(3*7)+(2*2)+(1*2)=116
116 % 10 = 6
So 74047-22-6 is a valid CAS Registry Number.
74047-22-6Relevant articles and documents
A rapid synthesis of lavendustin-mimetic small molecules by click fragment assembly
Yoon, Jieun,Ryu, Jae-Sang
supporting information; experimental part, p. 3930 - 3935 (2010/08/20)
Lavendustin-mimetic small molecules modifying the linker -CH 2-NH- with an 1,2,3-triazole ring have been synthesized via a click chemistry. Two pharmacophoric fragments of lavendustin were varied to investigate chemical space and the auxophoric -CH2-NH- was altered to an 1,2,3-triazole for rapid click conjugation. The small molecules were evaluated against HCT116 colon cancer and CCRF-CEM leukemia cell lines. Among 28 analogues, 3-phenylpropyl ester 26b inhibited CCRF-CEM leukemia cell growth with GI50 value of 0.9 μM.
