74068-80-7

Basic information

• Product Name: 5-(2-{Benzyl-[1-(4-cyclohexyl-phenyl)-ethyl]-amino}-acetyl)-2-benzyloxy-benzoic acid methyl ester
• CAS NO: 74068-80-7
• Molecular Weight: 575.748
• Mol File: 74068-80-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(2-{Benzyl-[1-(4-cyclohexyl-phenyl)-ethyl]-amino}-acetyl)-2-benzyloxy-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-{Benzyl-[1-(4-cyclohexyl-phenyl)-ethyl]-amino}-acetyl)-2-benzyloxy-benzoic acid methyl ester(74068-80-7)
• EPA Substance Registry System: 5-(2-{Benzyl-[1-(4-cyclohexyl-phenyl)-ethyl]-amino}-acetyl)-2-benzyloxy-benzoic acid methyl ester(74068-80-7)

Safety Data

• Hazardous Substances Data: 74068-80-7(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 27475-09-8 5-acetyl-2-benzyloxybenzoic acid methyl ester 
• 16475-90-4 estere metilico dell'acido 5-acetilsalicilico 
• 27475-14-5 2-benzyloxy-5-(2-bromoacetyl)benzoic acid methyl ester 
• 74068-21-6 α-metil-4-cicloesil-N-benzilbenzilammina 

Relevant articles and documents

SINTESI E STUDIO FARMACOLOGICO DI DERIVATI DELL'ORCIPRENALINA E DEL SALBUTAMOLO

The effect of replacing the basic aliphatic residue of orciprenaline and salbutamol with: a) a heterocyclic amine; b) a basic residue containing a phenylcyclohexane radical has been studied.The synthesis of the compounds is outlined.They were tested in vitro for relaxation of histamine-induced spasm of tracheal chains and on the isolated Langendorff heart, and in vivo according to the Konzett and Roessler technique and for their action on the cardiovascular system.In all tests the new derivatives were less active than the reference substances; the only exception was (A) where R = 4-phenylpiperidine (M.G.6604), which was almost as active as orciprenaline in the Konzett and Roessler test, had one third of its activity on isolated trachea and showed absolutely no influence on heart rate in vitro or in vivo.Its effect was not inhibited by β-blocking agents; it therefore showed as antihistaminic profile.