74080-68-5

Basic information

• Product Name: (R)-(-)-<2',6',8-3H3>reticuline
• CAS NO: 74080-68-5
• Molecular Weight: 335.372
• Mol File: 74080-68-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-(-)-<2',6',8-3H3>reticuline(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-<2',6',8-3H3>reticuline(74080-68-5)
• EPA Substance Registry System: (R)-(-)-<2',6',8-3H3>reticuline(74080-68-5)

Safety Data

• Hazardous Substances Data: 74080-68-5(Hazardous Substances Data)

Upstream product

• 485-19-8 (R)-reticuline 

Relevant articles and documents

Enzymic synthesis of glaucine in cell free system from Litsea glutinosa

The bioconversion of 1-benzyltetrahydroisoquinolines such as norcoclaurine (1), coclaurine (2), N-methylcoclaurine (3), 6-methoxynorlaudanosoline (4), 6-methoxylaudanosoline (5) and reticuline (6) and aporphine alkaloids isoboldine (11), thaliporphine (12) and N-methyllaurotetanine (13) into glaucine (14) in the cell free system from Litsea glutinosa (Lour) C.B.Rob. var. glabraria Hook f. (Lauraceae) has been studied.Stereospecificity of enzymes has been demonstrated by parallel incubation of (S)-(+)-, and (R)-(-)-reticulines.The incubation experiments reveal thatglaucine is synthesized by trihydroxylated base.N-Methylation of 2 is preferred over aryl hydroxylation to form 6 which by oxidative coupling forms 11 and methylation via 12 gives glaucine (14).