741693-88-9

Basic information

• Product Name: 2-Naphthalenol,5-fluoro-(9CI)
• Synonyms: 2-Naphthalenol,5-fluoro-(9CI);5-Fluoro-2-naphthalenol;2-Naphthalenol,5-fluoro-
• CAS NO: 741693-88-9
• Molecular Formula: C10H7FO
• Molecular Weight: 162.1603832
• Product Categories: HALIDE;Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 741693-88-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: Chloroform, Dichloromethane, DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 2-Naphthalenol,5-fluoro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Naphthalenol,5-fluoro-(9CI)(741693-88-9)
• EPA Substance Registry System: 2-Naphthalenol,5-fluoro-(9CI)(741693-88-9)

Safety Data

• Hazardous Substances Data: 741693-88-9(Hazardous Substances Data)

Usage

Description

2-Naphthalenol,5-fluoro-(9CI) is an organic compound derived from naphthalene, a type of polycyclic aromatic hydrocarbon. It is characterized by the presence of a hydroxyl group at the 2nd position and a fluorine atom at the 5th position on the naphthalene ring. 2-Naphthalenol,5-fluoro-(9CI) is known for its unique chemical properties and potential applications in various industries.

Uses

Used in Pharmaceutical Industry:
2-Naphthalenol,5-fluoro-(9CI) is used as a reactant for the preparation of Duloxetine metabolites. Duloxetine, with the CAS number D721000, is a widely prescribed medication for the treatment of various conditions, including depression, anxiety, and neuropathic pain. 2-Naphthalenol,5-fluoro-(9CI) plays a crucial role in the synthesis of these metabolites, which are essential for understanding the drug's pharmacokinetics and pharmacodynamics.
In the preparation of Duloxetine metabolites, 2-Naphthalenol,5-fluoro-(9CI) serves as a key intermediate, contributing to the development of new pharmaceutical compounds with improved efficacy and safety profiles. Its unique chemical structure allows for further functionalization and modification, enabling the creation of novel drug candidates with potential therapeutic benefits.

Upstream product

• 86-97-5 5-amino-2-naphthol 
• 853192-61-7 6-hydroxynaphthalene-1-diazonium tetrafluoroborate 

Downstream Products

• 853192-64-0 1-fluoro-6-methoxynaphthalene 
• 741693-89-0 1-fluoro-6-methoxynaphth-5-ol 
• 741693-79-8 2-Methoxy-5-((S)-3-methylamino-1-thiophen-2-yl-propoxy)-naphthalen-1-ol 
• 1552321-24-0 C₂₇H₂₄FN₃O₄S 
• 1552320-93-0 2-[4-[[2-(5-fluoro-2-naphthyl)-5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-4-yl]amino]phenyl]acetic acid sodium salt 

Relevant articles and documents

ANTIPROLIFERATIVE BENZO [B] AZEPIN- 2 - ONES

Disclosed are compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein W, X, Y, Z, R1, R2, R3 and R4 are described in this application, and methods of using said compounds in the treatment of cancer.