741709-19-3

Basic information

• Product Name: 1H-Indole-5-carbonitrile, 1-methyl-2-phenyl-
• CAS NO: 741709-19-3
• Molecular Formula: C16H12N2
• Molecular Weight: 232.285
• Mol File: 741709-19-3.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1H-Indole-5-carbonitrile, 1-methyl-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-5-carbonitrile, 1-methyl-2-phenyl-(741709-19-3)
• EPA Substance Registry System: 1H-Indole-5-carbonitrile, 1-methyl-2-phenyl-(741709-19-3)

Safety Data

• Hazardous Substances Data: 741709-19-3(Hazardous Substances Data)

Usage

Organic compound

1H-Indole-5-carbonitrile, 1-methyl-2-phenylis an organic compound, meaning it is primarily composed of carbon, hydrogen, and other elements such as nitrogen.

Indole class of compounds

This compound belongs to the indole class of compounds, which are known for their diverse biological activities.

Pharmaceutical and agrochemical synthesis

This chemical is commonly used in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds.

Potential applications in drug discovery

1H-Indole-5-carbonitrile, 1-methyl-2-phenylhas been studied for its potential applications in drug discovery and development due to its unique chemical structure and properties.

Exhibits interesting biological activities

This compound has been found to exhibit interesting biological activities, making it a valuable compound for further research in the fields of medicinal chemistry and chemical biology.

Upstream product

• 91634-11-6 N-methyl-5-cyanoindole 
• 591-50-4 iodobenzene 
• 15861-24-2 1H-indole-5-carbonitrile 
• 98-80-6 phenylboronic acid 

Relevant articles and documents

C2–H Arylation of Indoles Catalyzed by Palladium-Containing Metal-Organic-Framework in γ-Valerolactone

An efficient and selective procedure was developed for the direct C2–H arylation of indoles using a Pd-loaded metal–organic framework (MOF) as a heterogeneous catalyst and the nontoxic biomass-derived solvent γ-valerolactone (GVL) as a reaction medium. The developed method allows for excellent yields and C-2 selectivity to be achieved and tolerates various substituents on the indole scaffold. The established conditions ensure the stability of the catalyst as well as recoverability, reusability, and low metal leaching into the solution.

NaNO2/K2S2O8-mediated Selective Radical Nitration/Nitrosation of Indoles: Efficient Approach to 3-Nitro- and 3-Nitrosoindoles

JPZ acknowledges financial support from the National Natural Science Foundation of China (No. 21172163, 21472133), the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD), and Key Laboratory of Organic Synthesis of Jiangsu Province (KJS1749). (Figure presented.).

A highly efficient and recyclable Fe3O4 magnetic nanoparticle immobilized palladium catalyst for the direct C-2 arylation of indoles with arylboronic acids

A highly efficient Fe3O4 magnetic nanoparticle (MNP) immobilized palladium catalyst was prepared and applied to the direct C-2 arylation of indoles with arylboronic acids. The reactions generated the corresponding cross-coupling products in good yields. In addition, the supported catalyst with low loading (2.0 mol%) showed high stability and could be recovered and reused 8 times without significant loss of activity. The Royal Society of Chemistry 2014.