7418-66-8

Basic information

• Product Name: 4-AMINO-3-PYRIDINECARBOXAMIDE
• Synonyms: 4-AMINO-3-PYRIDINECARBOXAMIDE;3-Pyridinecarboxamide,4-amino-(9CI);4-aminonicotinamide;4-Aminopyridine-3-carboxamide;4-Amino-3-pyridinecarboxa...;4-AMino-3-pyridinecarboxaMide hydrochloride
• CAS NO: 7418-66-8
• Molecular Formula: C₆H₇N₃O
• Molecular Weight: 137.13928
• Product Categories: AMIDE;Pyridine;Building Blocks;Heterocycle-Pyridine series
• Mol File: 7418-66-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 229.5-230.5 °C
• Boiling Point: 377.8 °C at 760 mmHg
• Flash Point: 182.3 °C
• Appearance: off-white to light yellow crystal powder
• Density: 1.323 g/cm³
• Vapor Pressure: 6.6E-06mmHg at 25°C
• Refractive Index: 1.643
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 14.60±0.50(Predicted)
• CAS DataBase Reference: 4-AMINO-3-PYRIDINECARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-3-PYRIDINECARBOXAMIDE(7418-66-8)
• EPA Substance Registry System: 4-AMINO-3-PYRIDINECARBOXAMIDE(7418-66-8)

Safety Data

• Hazard Codes: Xn
• Hazardous Substances Data: 7418-66-8(Hazardous Substances Data)

Usage

Chemical Properties

off-white to light yellow crystal powder

InChI:InChI=1/C6H7N3O/c7-5-1-2-9-3-4(5)6(8)10/h1-3H,(H2,7,9)(H2,8,10)

Upstream product

• 16135-36-7 methyl 4-aminonicotinate 
• 104915-67-5 4-aminonicotinoyl azide 
• 5977-14-0 acetoacetamido 
• 17758-33-7 3-methyl-5-nitro-4(3H)-pyrimidinone 
• 89533-20-0 4-aminonicotinoyl hydrazide 
• 7418-65-7 4-aminonicotinic acid 

Downstream Products

• 1303528-59-7 1-{[2-(4-phenoxyphenoxy)ethoxy]methyl}-3-aminocarbonyl-4-aminopyridinium chloride 
• 1428732-40-4 C₂₀H₂₄N₄O₄ 
• 1428732-41-5 C₂₆H₂₄ClN₅O 
• 1437181-26-4 C₂₀H₂₂N₄O₃ 

Relevant articles and documents

POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS

The present invention is related to a pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent and a compound represented by the following structural formula: The present invention is also related a method of treating a subject with a disease which can be ameliorated by inhibition of poly(ADP-ribose)polymerase (PARP). The definitions of the variables are provided herein.

Ring-Opening Reactions of Triazolo- and Tetrazolo-Pyridopyrimidines or Quinazolines with some Carbon Nucleophiles

Syntheses of some new pyridotriazolo- and pyridotetrazolopyrimidines are described.These tricyclic systems and tetrazoloquinazoline react with some carbon nucleophiles, generated from compounds with reactive methylene groups, exclusively at position 2 of