742076-06-8

Basic information

• Product Name: 1-(4-PIPERIDINYL)-2-(TRIFLUOROMETHYL)-1H-BENZIMIDAZOLE
• Synonyms: 1-(4-PIPERIDINYL)-2-(TRIFLUOROMETHYL)-1H-BENZIMIDAZOLE;1-(Piperidin-4-yl)-2-(trifluoroMethyl)-1H-benzo[d]iMidazole;1-piperidin-4-yl-2-(trifluoromethyl)benzimidazole;1-(Piperidin-4-yl)
• CAS NO: 742076-06-8
• Molecular Formula: C13H14F3N3
• Molecular Weight: 269.27
• Mol File: 742076-06-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 354.9°C at 760 mmHg
• Flash Point: 168.4°C
• Appearance: /
• Density: 1.41g/cm³
• Vapor Pressure: 3.25E-05mmHg at 25°C
• Refractive Index: 1.597
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 1-(4-PIPERIDINYL)-2-(TRIFLUOROMETHYL)-1H-BENZIMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-PIPERIDINYL)-2-(TRIFLUOROMETHYL)-1H-BENZIMIDAZOLE(742076-06-8)
• EPA Substance Registry System: 1-(4-PIPERIDINYL)-2-(TRIFLUOROMETHYL)-1H-BENZIMIDAZOLE(742076-06-8)

Safety Data

• Hazardous Substances Data: 742076-06-8(Hazardous Substances Data)

Usage

General Description

1-(4-piperidinyl)-2-(trifluoromethyl)-1H-benzimidazole is a chemical compound with potential pharmacological properties. It belongs to the class of benzimidazole compounds and contains a piperidine ring and a trifluoromethyl group. 1-(4-PIPERIDINYL)-2-(TRIFLUOROMETHYL)-1H-BENZIMIDAZOLE has shown potential as an antipsychotic and anxiolytic agent in preclinical studies. It is believed to act as a serotonin receptor agonist, particularly targeting the 5-HT1A receptor, which is involved in the regulation of mood and anxiety. Additionally, the trifluoromethyl group may confer enhanced metabolic stability and membrane permeability to the molecule, making it a promising candidate for further investigation in the development of new treatments for psychiatric disorders.

InChI:InChI=1/C13H14F3N3/c14-13(15,16)12-18-10-3-1-2-4-11(10)19(12)9-5-7-17-8-6-9/h1-4,9,17H,5-8H2