74308-05-7

Basic information

• Product Name: ethyl 9-oxo-6,9-dihydro-3H-imidazo[4,5-f]quinoline-8-carboxylate
• CAS NO: 74308-05-7
• Molecular Formula: C₁₃H₁₁N₃O₃
• Molecular Weight: 257.2447
• Mol File: 74308-05-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 541°C at 760 mmHg
• Flash Point: 281°C
• Density: 1.43g/cm³
• Vapor Pressure: 9.09E-12mmHg at 25°C
• Refractive Index: 1.673
• CAS DataBase Reference: ethyl 9-oxo-6,9-dihydro-3H-imidazo[4,5-f]quinoline-8-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 9-oxo-6,9-dihydro-3H-imidazo[4,5-f]quinoline-8-carboxylate(74308-05-7)
• EPA Substance Registry System: ethyl 9-oxo-6,9-dihydro-3H-imidazo[4,5-f]quinoline-8-carboxylate(74308-05-7)

Safety Data

• Hazardous Substances Data: 74308-05-7(Hazardous Substances Data)

Upstream product

• 58842-46-9 3-(5-benzimidazolyl)amino-2-ethoxycarbonyl-prop-2-enoic acid ethyl ester 

Downstream Products

• 233-55-6 imidazo<4,5-f>quinoline 
• 82723-47-5 3,6-Dihydro-imidazo[4,5-f]quinolin-9-one 

Relevant articles and documents

THERMAL CYCLOCONDENSATIONS OF 3-N(4- AND 5-BENZIMIDAZOLYL AND BENZTRIAZOLYL)AMINO DERIVATIVES OF 2-PROPENOIC ACID

The cyclization of 3-N-(4- and 5-benzimidazolyl and benztriazolyl)amino-2-cyano- and 2-ethoxycarbonyl-2-propenoate esters Ia,b-IVa,b under the conditions of the Gould-Jacobs reaction leads to angularly ring-fused substituted imidazo or triazolo (V, VI) and (VII, VIII) quinolines, respectively.The esters Vb-VIIIb have been transformed into the corresponding chloroderivatives Vc-VIIIc. 3-N(5-Benzimidazolyl and 5-benztriazolyl)amino-2-cyano-2-propenenitriles are cyclized in the presence of aluminium(III) chloride to give the aminoquinolines Vd, VId.The structure of the products has been characterized by their 1H, 13C NMR, IR, and UV spectra.