74317-53-6Relevant articles and documents
Water-soluble rhodamine-based chemosensor for Fe3+ with high sensitivity, selectivity and anti-interference capacity and its imaging application in living cells
Zhou, Feng,Leng, Tao-Hua,Liu, Ya-Jing,Wang, Cheng-Yun,Shi, Ping,Zhu, Wei-Hong
, p. 429 - 436 (2017)
Fe3+ plays a crucial role in many vital cell functions and its detection has attracted considerable attention. In this work, a water-soluble rhodamine-based chemosensor RL has been designed and synthesized as an “off-on” chemosensor for Fe
Visible light excitable on fluorescence and naked eye detection of Cu 2+via hydrolysis of rhodamine-thiophene conjugate: Human breast cancer cell (MCF7) imaging studies
Adhikari, Sangita,Ghosh, Abhijit,Mandal, Sandip,Sengupta, Archya,Chattopadhyay, Ansuman,Sanmartin Matalobos, Jesus,Lohar, Sisir,Das, Debasis
, p. 7747 - 7751 (2014)
Thiophene appended rhodaminehydrazone derivative, RDHDTCA allows selective colorimetric and fluorescence recognition of Cu2+ as low as 2.4 × 10-8 M. RDHDTCA is capable to detect intracellular Cu 2+ in human breast cancer c
Rhodamine-azobenzene based single molecular probe for multiple ions sensing: Cu2+, Al3+, Cr3+ and its imaging in human lymphocyte cells
Mabhai, Subhabrata,Dolai, Malay,Dey, Surya Kanta,Dhara, Anamika,Choudhury, Sujata Maiti,Das, Bhriguram,Dey, Satyajit,Jana, Atanu
, p. 319 - 332 (2019)
A photoinduced electron transfer (PET) and chelation-enhanced fluorescence (CHEF) regulated rhodamine-azobenzene chemosensor (L) was synthesized for chemoselective detection of Al3+, Cr3+, and Cu2+ by UV–Visible absorption study whereas Al3+ and Cr3+ by fluorimetric study in EtOH-H2O solvent. L showed a clear fluorescence emission enhancement of 21 and 16 fold upon addition of Al3+ and Cr3+ due to the 1:1 host-guest complexation, respectively. This is first report on rhodamine-azobenzene based Cr3+ chemosensor. The complex formation, restricted imine isomerization, inhibition of PET (photo-induced electron transfer) process with the concomitant opening of the spirolactam ring induced a turn-on fluorescence response. The higher binding constants 6.7 × 103 M?1 and 3.8 × 103 M?1 for Al3+ and Cr3+, respectively and lower detection limits 1 × 10?6 M and 2 × 10?6 M for Al3+ and Cr3+, respectively in a buffered solution with high reversible nature describes the potential of L as an effective tool for detecting Al3+ and Cr3+ in a biological system with higher intracellular resolution. Finally, L was used to map the intracellular concentration of Al3+ and Cr3+ in human lymphocyte cells (HLCs) at physiological pH very effectively. Altogether, our findings will pave the way for designing new chemosensors for multiple analytes and those chemosensors will be effective for cell imaging study.
The influences of different substituents on spectral properties of rhodamine B based chemosensors for mercury ion and application in EC109 cells
Du, Wenqi,Cheng, Yu,Shu, Weixin,Wu, Baoying,Kong, Zhineng,Qi, Zhengjian
, p. 751 - 757 (2017)
Six rhodamine-based "turn-on" fluorescence chemosensors (L1-L6) with different substituents for mercury (Hg2+) were readily synthesized and investigated; they displayed high selectivity and chelation enhanced ratiometric f
A rhodamine-based dual chemosensor for the naked-eye detection of Hg2+and enhancement of the fluorescence emission for Fe3+
Hu, Jian-Peng,Yang, Hao-Hang,Lin, Qi,Yao, Hong,Zhang, You-Ming,Wei, Tai-Bao,Qu, Wen-Juan
, p. 1690 - 1696 (2020)
A novel fluorescent chemosensor based on trimesoyl chloride-rhodamine (TR) was successfully synthesized. Rising chromogenic and fluorogenic spectral enhancements could be observed in trimesoyl chloride-rhodamine (TR) probes when Hg2+ and Fe3+ were added, respectively. TR has shown selectivity for Hg2+ and Fe3+ with high sensitivity due to metal ion complexation induced photophysical "turn-on"signaling responses. The detection limit towards Hg2+ was 2.46 × 10-8 M as determined by the 3σ method. At the same time, fluorogenic spectral enhancements were observed in TR, which exhibits a superior sensitive and selective recognition towards Fe3+ with 4.11 × 10-8 M of the detection limit. The test strips were used for colorimetric and simple detection towards Hg2+, which might finally enable the advancement of the Hg2+ sensor in the field of on-site detection. This journal is
Rhodamine B conjugate for rapid colorimetric and fluorimetric detection of aluminium and tin ions and its application in aqueous media
Cheah, Poh Wei,Heng, Mok Piew,Izati, Amnor,Ng, Chew Hee,Tan, Kong Wai
, (2020)
A new fluorescent chemosensor (MEK) was synthesized from conjugation of rhodamine B hydrazide and methyl ethyl ketone. It exhibited features that would facilitate the ‘naked-eye’ detection, including excellent selectivity and high sensitivity towards Al3+ and Sn2+ ions. Stronger binding strength was recorded in the formation of sensor-Al3+ complex, where the binding constant (Ka) was 3.58 × 1010 M?1. Detection limits of MEK for Sn2+ and Al3+ was 5.10 μM and 8.96 μM respectively. Moreover, a 1:2 and 1:1 binding stoichiometry between this sensor with Al3+ and Sn2+ was verified via Job's plot and ESI-MS. Reversibility of the sensor as metal ions detector was evaluated with the introduction of the common quencher EDTA and it showed that MEK can be used repeatedly up to 6 times. Differences in the fluorescence profiles of sensor and the sensor-metal complexes (Al3+ and Sn2+) suggested the possible applications of MEK as detection kit for these metal ions. Interestingly, the on-site assay study shown obvious colour changes and fluorescence, thereby reflecting a potentially useful way in differentiating Al3+ and Sn2+. The combination of significant fluorescence response along with tunable selectivity is therefore notably practical for the application of this sensor.
Toward a highly sensitive and selective indole-rhodamine-based light-up probe for Hg2+ and its application in living cells
Tang, Yao,Jiang, Guo-Fang
, p. 2846 - 2849 (2017)
We herein designed and synthesized a light-up fluorescent probe L1 for Hg2+ species, which is based on indole derivative and Rhodamine fluorophore. The new probe can show a linear response to Hg2+ with high sensitivity and selectivity. As the Hg2+ concentration changed from 0 to 450?μM, the fluorescence intensity of L1 at 575?nm changed from 50 to 6181 (～120-fold). The detection limit of the probe was 5.0?×?10?8?M. Besides, we have successfully applied L1 to monitor Hg2+ species in living MCF-7 cells by way of fluorescence imaging.
A selective turn-on fluorescent sensor for FeIII and application to bioimaging
Zhang, Meng,Gao, Yanhong,Li, Manyu,Yu, Mengxiao,Li, Fuyou,Li, Lei,Zhu, Minwei,Zhang, Jianping,Yi, Tao,Huang, Chunhui
, p. 3709 - 3712 (2007)
A novel compound FD1 was demonstrated as a turn-on fluorescent sensor for imaging of iron(III) ion in biological samples. Based on the spirolactam (nonfluorescence) to ring-open amide (fluorescence) equilibrium, FD1 exhibited high selectivity and sensitiv
A new bis(rhodamine)-based colorimetric chemosensor for Cu2+
Abebe, Fasil,Gonzalez, Jazmin,Makins-Dennis, Khalil,Shaw, Roosevelt
, (2020)
A novel sensor (RD) bearing rhodamine B and 4-tert-Butyl phenol unit have been designed and synthesized using microwave irradiation. The sensor allows selective detection of Cu2+ by forming absorptive complex and trigger the formation of highly colored ring-open spirolactam. The recognition ability of the sensor was investigated by absorbance, Job's plot, nuclear magnetic resonance (NMR), infrared (IR) and time dependent-density functional theory (TD-DFT) calculations.
Semi-quantitative colorimetric and supersensitive electrochemical sensors for mercury using rhodamine b hydrazide thio derivative
Pramanik, Krishnendu,Sarkar, Priyabrata,Bhattacharyay, Dipankar
, p. 141 - 152 (2019)
Mercury is a toxic heavy metal which pollutes air, land, and water posing a serious threat to the environment and human health. For a first-hand estimate, a qualitative method (colorimetric) for detection of mercury could suffice. However for precise measurement, below the threshold value, a quantitative method (electrochemical) is needed. The colorimetric strips were produced using mercapto-propionic acid derivatized rhodamine hydrazide (RS). RS developed a pink color when in contact with mercury (Hg2+) and the shade became darker with an increase in concentration. A new polymeric hydrogel was used to entrap RS to fabricate sensing strips for quasi-quantitative detection of Hg2+ through the naked eye. An electrochemical sensor was also developed for accurate quantification of Hg2+ at ppt level by modified glassy carbon electrode with the same RS and green reduced graphene oxide (RS-gRGO/GCE) via differential pulse anodic stripping voltammetry (DPASV). The dipstick exhibited high sensitivity, good selectivity and low detection limit (0.29 ppb) whereas metal free, label-free modified electrode performed very well with a high sensitivity (70.22 μA·ppb·cm?2), low detection limit (57 ppt), good selectivity, and reproducibility. These sensors will serve the purpose of common people for onsite estimation as well as scientific laboratories requiring precision measurements.
PKa Modulation in rhodamine based probes for colorimetric detection of picric acid
Nagarajan,Bag, Bamaprasad
, p. 9510 - 9513 (2014)
Tuning the pKa in acid sensitive rhodamine spirolactam derivatives as a function of the solvent medium resulted in the selective detection of picric acid from its lower nitro phenolic analogues and a few other carboxylic acids. This journal is
A novel highly selective colorimetric and “turn-on” ?uorimetric chemosensor for detecting Hg2+ based on Rhodamine B hydrazide derivatives in aqueous media
Hu, Jing-Han,Long, Chen,Fu, Qing-Qing,Ni, Peng-Wei,Yin, Zhi-Yuan
, p. 105 - 111 (2019)
A novel chemical sensor SD based on Rhodamine B hydrazide derivative was designed and synthesized, which displayed both colorimetric and “turn-on” ?uorescence responses for Hg2+ in DMSO/H2O (1: 9, v/v) solution. In the presence of me
Rhodamine-modified upconversion nanoprobe for distinguishing Cu2+ from Hg2+ and live cell imaging
Xu, Yanxia,Li, Huifang,Meng, Xianfu,Liu, Jinliang,Sun, Lining,Fan, Xiaolin,Shi, Liyi
, p. 3543 - 3551 (2016)
It is greatly important to seek a fast and sensitive method for the detection of Cu2+ ions because of their vital role in the human body. Fluorescent probes, especially the rhodamine derivatives, have been considered as promising candidates for detection of Cu2+ ions due to their attractive features. However, one problem frequently encountered in rhodamine-based fluorescent probes is that some of them could not distinguish Cu2+ from Hg2+ and these drawbacks limit their application in biological samples. In this paper, a rhodamine B derivative (RBH) was grafted to mesoporous silica coated upconversion nanoparticles (CS-UCNP) to fabricate a new organic-inorganic hybrid nanoprobe. On addition of Cu2+ ions, an emission band at about 580 nm appeared while the intensity of the green emission at about 545 nm of the nanoprobe decreased upon excitation of a 980 nm laser, implying that a luminescence resonance energy transfer (LRET) happened from the CS-UCNP to the RBH-Cu2+ complex. The obtained LRET nanoprobe could detect Cu2+ exclusively even in the presence of Hg2+ with a detection limit of 0.82 μM in absolute ethanol solution. Most importantly, this nanoprobe can be used for monitoring subcellular distribution of Cu2+ in living cells based on upconversion luminescence and downconversion fluorescence.
A selective and sensitive off–on probe for palladium and its application for living cell imaging
Long, Ying,Zhou, Jia,Yang, Mei-Pan,Yang, Bing-Qin
, p. 205 - 210 (2016)
A new rhodamine B derivative T1 has been rationally synthesized and displayed selective Pd(II)-amplified absorbance and fluorescence emission above 540 nm in methanol–water. Upon the addition of Pd(II), the spirolactam ring was unfolded and a 1:1 metal-ligand complex formed, which can be used for “naked-eyes” detection. In addition, fluorescence imaging experiments of Pd2+ in HepG2 living cells showed its valuable application in biological systems.
A new off-on fluorescent probe for Al3+ in aqueous solution based on rhodamine B and its application to bioimaging
Huang, Qi,Zhang, Qingyou,Wang, Enze,Zhou, Yanmei,Qiao, Han,Pang, Lanfang,Yu, Fang
, p. 70 - 76 (2016)
In this paper, a new fluorescent probe has been synthesized and applied as off-on sensor for the detection of Al3+ with a high sensitivity and excellent selectivity in aqueous media. The sensor was easily prepared by one step reaction between rhodamine B hydrazide and pyridoxal hydrochloride named RBP. The structure of the sensor has been characterized by nuclear magnetic resonance and electron spray ionization-mass spectrometry. The fluorescence intensity and absorbance for the sensor showed a good linearity with the concentration of Al3+ in the range of 0-12.5 μM and 8-44 μM, respectively, with detection limits of 0.23 μM and 1.90 μM. The sensor RBP was preliminarily applied to the determination of Al3+ in water samples from the lake of Henan University and tap water with satisfying results. Moreover, it can be used as a bioimaging reagent for imaging of Al3+ in living cells.
Spiroguanidine rhodamines as fluorogenic probes for lysophosphatidic acid
Wang, Lei,Sibrian-Vazquez, Martha,Escobedo, Jorge O.,Wang, Jialu,Moore, Richard G.,Strongin, Robert M.
, p. 1697 - 1700 (2015)
Direct determination of total lysophosphatidic acid (LPA) was accomplished using newly developed spiroguanidines derived from rhodamine B as universal fluorogenic probes. Optimum conditions for the quantitative analysis of total LPA were investigated. The
A FRET-based rhodamine-benzimidazole conjugate as a Cu2+- selective colorimetric and ratiometric fluorescence probe that functions as a cytoplasm marker
Goswami, Shyamaprosad,Maity, Sibaprasad,Maity, Annada C.,Maity, Anup Kumar,Das, Avijit Kumar,Saha, Partha
, p. 6300 - 6305 (2014)
On the basis of fluorescence resonance energy transfer (FRET) from benzimidazole to a rhodamine moiety, a rhodamine-benzimidazole conjugate (RBC) ratiometric fluorescent probe has been designed and synthesized. The RBC selectively binds to Cu2+, showing visually observable changes in absorption and emission behavior, and demonstrates an effective intracellular Cu2+ imaging ability, allowing it to function as a cytoplasm marker.
Multifunctional Fe3O4@SiO2 nanoparticles for selective detection and removal of Hg2+ ion in aqueous solution
Sun, Zebin,Guo, Dan,Li, Haizhen,Zhang, Li,Yang, Bo,Yan, Shiqiang
, p. 11000 - 11008 (2015)
In the present work, a multifunctional magnetic core-shell Fe3O4@SiO2 nanoparticle decorated with a rhodamine-based receptor, which exhibits high selectivity and sensitivity toward Hg2+ over other metal ions in aqueous solution, has been synthesized by the graft method and characterized by transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, vibrating sample magnetometry, and UV-vis absorption and fluorescence spectra. The multifunctional nanoparticles show superparamagnetic behavior, clear core-shell architecture, and also exhibit high optical sensing performance for the detection of Hg2+. The fluorogenical responses of RB-Fe3O4@SiO2 are stable under a broad pH range. Additionally, these nanoparticles show high performance in the magnetic separability and effective removal of excess Hg2+ in water via an external magnetic field. These results indicate that these multifunctional magnetic nanoparticles may find potential and practical applications for selective detection and simple removal of Hg2+ in environmental, toxicological, and biological fields.
Single crystal X-ray structurally characterized palladium(II) selective fluorescence and colorimetric indicator for human breast cancer cell imaging
Ghosh, Abhijit,Nandi, Sandip,Sengupta, Archya,Chattopadhyay, Ansuman,Lohar, Sisir,Das, Debasis
, p. 52 - 56 (2015)
Abstract Condensation of rhodamine B hydrazide with 4-formylbenzonitrile generates a Pd2+ selective probe (RDHDNB) that allows its naked eye and fluorescence recognition. Moreover, RDHDNB is useful to detect Pd2+ in human breast cancer cells MCF7, under normal and fluorescence microscope.
A highly sensitive “Off-On” optical and fluorescent chemodosimeter for detecting iron (III) and its application in practical samples: An investigation of Fe3+ induced oxidation by mass spectrometry
Sirajuddin Nayab, Pattan,Shkir, Mohd.,Gull, Parveez,AlFaify
, p. 209 - 217 (2017)
We describe a highly sensitive turn on colorimetric and fluorescent probe for trivalent iron ions (Fe3+). The newly synthesized compound (RCD) was characterized by FTIR, NMR and mass spectral studies. Competitive experiments reveal that probe R
Fluorescent Polyamide-Based Rhodamine Hydrazide Moieties with Oxethyl as Spacer for Detection of Cr3+, Fe3+, and Hg2+ Ions in Water
Geng, Tong-Mou,Wang, Xie,Jiang, Hui,Song, Wan,Ni, Ruo-Fan,Chen, Jian,Wang, Yu
, p. 977 - 985 (2016)
An acrylic monomer bearing xanthene group, N-oxethyl acrylate-N′-rhodamine B hydrazide (ARBHE) was synthesized from N-hydroxyl ethyl-N′-rhodamine hydrazide (RBHE) and acryloyl chloride (Ac) in the presence of triethylamine in dry dichloromethane (CH2Cl2) at room temperature. The synthesized ARBHE was identified by FTIR, 1H NMR spectra and elementary analysis. Copolymer poly(AM-ARBHE) of ARBHE and AM was synthesized with thermal initiator by free radical precipitation polymerization and it was characterized by the method of FTIR and 1H NMR. Its molecular weights (Mη) was 7.03?×?103?g?mol?1 and the content of rhodamine units in the polymer chains was 1.44?% in mole fraction. The ability of the poly(AM-ARBHE) to detect different metal cations (Ag+, Ba2+, Cd2+ Co2+, Cr3+, Cu2+, Co2+ K+, La3+, Mg2+, Na+, Ni2+, Pb2+, Fe2+, Fe3+, Hg2+ and Zn2+) in water was investigated. Upon addition of Cr3+, Fe3+ or Hg2+ ions to the aqueous solution, visual color change and fluorescence enhancement were observed. Moreover, other metal ions did not induce obvious changes to the fluorescence spectra except to Fe2+. The detection limit of poly(AM-ARBHE) was less than 1?×?10?11?M. The results suggest that this copolymer may offer potential as a polymeric sensor for Cr3+, Fe3+ and Hg2+ ions in water.
A lysosome-targeted fluorescent sensor for the detection of glutathione in cells with an extremely fast response
Huang, Rong,Wang, Bei-Bei,Si-Tu, Xing-Ming,Gao, Tao,Wang, Fang-Fang,He, Huan,Fan, Xiao-Yang,Jiang, Feng-Lei,Liu, Yi
, p. 11579 - 11582 (2016)
A highly sensitive and selective Rhodamine B-based fluorescent sensor, RhB-1, for glutathione (GSH) was easily synthesized. An extremely fast detection response time of 10 s, which is the fastest one ever reported, is achieved in aqueous solutions over a wide pH range with large enhancement of emission intensity. The sensor detects GSH in cells and selectively accumulates in lysosomes.
From one to three, modifications of sensing behavior with solvent system: DFT calculations and real-life application in detection of multianalytes (Cu2+, Ni2+ and Co2+) based on a colorimetric Schiff base probe
Pungut, Nur Amira Solehah,Heng, Mok Piew,Saad, Hazwani Mat,Sim, Kae Shin,Lee, Vannajan Sanghiran,Tan, Kong Wai
, (2021)
A rhodamine-based colorimetric sensor, RBOV has been synthesized and modified for selective detection of Cu2+, Ni2+ and Co2+ ions simultaneously in aqueous medium. The difference in color change upon binding with these three cations makes it an interesting multianalyte sensor. Furthermore, the detection limits of RBOV for Cu2+, Ni2+ and Co2+ are down to 4.0 × 10?2 μM, 3.2 × 10?1 μM and 4.8 × 10?1 μM respectively. The possible sensing mechanism analyzed from Benesi-Hildebrand plot, Job's plot, FTIR and DFT studies showed a 1:1 stoichiometry of sensor-metal complex for all three analytes. Practical application of sensor was conducted in real time using test strips and MTT assay was conducted to determine its cytotoxicity.
An optical sensing composite for cysteine detection using up-conversion nanoparticles and a rhodamine-derived chemosensor: Construction, characterization, photophysical feature and sensing performance
Kai, Song,Cheng-Wen, Lu,Yi-Nan, Ding,Tian, Luan,Guang-Ye, Wang,Jing-Mei, Lu,Li-Quan, Guo
, p. 81 - 87 (2016)
In this paper, we reported an optical sensing composite for cysteine detection. A chemosensor derived from rhodamine 6G was synthesized and characterized. To minimize its photobleaching, up-conversion nanocrystals β-NaYF4:Yb3 +/Er3 + were prepared and modified with α-cyclodextrin, serving as excitation host. Under 980 nm laser excitation, emission of these up-conversion nanocrystals overlapped well with the absorption of our chemosensor. Energy transfer between them was analyzed and confirmed by emission decay analysis. Job's analysis suggested that the complexation equilibrium between our chemosensor and cysteine was a simple one with binding stoichiometry of 1:1. A sensing system was constructed with up-conversion nanocrystals (modified with α-cyclodextrin) and this chemosensor. Emission "turn-on" effect was observed only for cysteine but immune to other competing amino acids and thiols, showing a good selectivity.
A highly selective fluorescence sensor for Tin (Sn4+) and its application in imaging live cells
Wang, Qi,Li, Chunyan,Zou, Ying,Wang, Haoxuan,Yi, Tao,Huang, Chunhui
, p. 6740 - 6746 (2012)
A naphthalimide-rhodamine B derivative was synthesized as a fluorescence turn-ON chemodosimeter for Sn4+. A colour change and marked enhancement of fluorescence was found in the presence of Sn4+, Cu2+ and Cr3+ due to the ring open reaction of rhodamine and a fluorescence resonance energy transfer process. Addition of the strong chelating agent ethylenediaminetetraacetic acid disodium salt (EDTA) partly released the cation from the complex with Sn4+ and restored the yellow fluorescence. In addition, the compound can be used as a fluorescent probe for Sn4+ in biological systems and may act as a tool with which to study the physiological functions of tin or pathogenesis in the human body.
A rapid turn-on dual functional rhodamine B probe for aluminum (III) and copper (II) that can be utilised as a molecular logic gate and in water analysis
Chan, Wei Chuen,Lee, Vannajan Sanghiran,Saad, Hazwani Mat,Sim, Kae Shin,Tan, Kong Wai
, (2022/01/19)
The new sensor, R34 was prepared from the reaction of rhodamine B hydrazide and 3,4-dihydroxybenzaldehyde, and it was characterised by spectroscopic techniques and single crystal X-ray diffraction. Sensor R34 can detect Al3+/Cu2+through colorimetric and fluorometric methods in MeCN solution, which displayed a notable color change from colorless to pink in the presence of Al3+ and colorless to orange for Cu2+. Other than that, both Al3+/Cu2+caused orange fluorescence enhancement under UV-light. Besides, sensor R34 demonstrates good selectivity and sensitivity towards Al3+/Cu2+ with high association constant (Ka > 104 M?1) and limit of detection down to the nano molar level. The reversibility of the sensor is verified by using EDTA and the finding implies that probe R34 can be recycled. Moreover, binding mechanism of the metal complexes were studied through DFT calculations, Job's plot, 1H NMR and FT-IR spectroscopy. Using Al3+/Cu2+ and EDTA as chemical inputs and absorption signal at 560 nm as output, sensor R34 can be applied as an INHIBIT logic gate at molecular level. In addition, sensor R34 was examined for the ability to trace Al3+/Cu2+in two different water samples. Furthermore, cytotoxicity of the sensor towards CCD-18Co and HT-29 cell lines was evaluated with MTT assay.
Characterization of a Hg2+-selective fluorescent probe based on rhodamine b and its imaging in living cells
Wen, Shaobai,Yang, Mei,Yu, Chunwei,Zhang, Jun,Zhang, Wenting
, (2021/06/21)
A small organic molecule P was synthesized and characterized as a fluorometric and colorimetric dual-modal probe for Hg2+. The sensing characteristics of the proposed probe for Hg2+ were studied in detail. A fluorescent enhancing property at 583 nm (>30 fold) accompanied with a visible colorimetric change, from colorless to pink, was observed with the addition of Hg2+ to P in an ethanol-water solution (8:2, v/v, 20 mM HEPES, pH 7.0), which would be helpful to fabricate Hg2+-selective probes with “naked-eye” and fluorescent detection. Meanwhile, cellular experimental results demonstrated its low cytotoxicity and good biocompatibility, and the application of P for imaging of Hg2+ in living cells was satisfactory.
