74385-18-5

Basic information

• Product Name: 3,4-dimethoxy-(1'-hydroxy-1'-methylethyl)benzene
• Synonyms: 3,4-dimethoxy-(1'-hydroxy-1'-methylethyl)benzene
• CAS NO: 74385-18-5
• Molecular Weight: 196.246
• Mol File: 74385-18-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3,4-dimethoxy-(1'-hydroxy-1'-methylethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dimethoxy-(1'-hydroxy-1'-methylethyl)benzene(74385-18-5)
• EPA Substance Registry System: 3,4-dimethoxy-(1'-hydroxy-1'-methylethyl)benzene(74385-18-5)

Safety Data

• Hazardous Substances Data: 74385-18-5(Hazardous Substances Data)

Upstream product

• 917-54-4 methyllithium 
• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 
• 326-56-7 methyl 3,4-methylenedioxybenzoate 
• 89980-69-8 3,4-dimethoxyphenylmagnesium bromide 
• 67-64-1 acetone 
• 2150-38-1 methyl 3,4-dimethoxybenzoate 
• 74-88-4 methyl iodide 
• 4132-76-7 1-isopropyl 3,4-dimethoxy benzene 
• 917-64-6 methyl magnesium iodide 
• 3943-77-9 ethyl veratrate 

Downstream Products

• 1448464-73-0 9-(2-isopropyl-4,5-dimethoxybenzyl)-9H-purine-2,6-diamine 
• 1448464-65-0 2-isopropyl-4,5-dimethoxybenzyl methanesulfonate 
• 1448464-64-9 (2-isopropyl-4,5-dimethoxyphenyl)methanol 
• 34582-07-5 2-isopropyl-4,5-dimethoxybenzaldehyde 
• 1448464-71-8 6-chloro-7-(2-isopropyl-4,5-dimethoxybenzyl)-7H-purin-2-amine 
• 4132-76-7 1-isopropyl 3,4-dimethoxy benzene 
• 1448464-81-0 7-(2-isopropyl-4,5-dimethoxybenzyl)-N⁶-methyl-7H-purine-2,6-diamine 
• 1448464-80-9 9-(2-isopropyl-4,5-dimethoxybenzyl)-N⁶-methyl-9H-purine-2,6-diamine 
• 1448464-78-5 7-(2-isopropyl-4,5-dimethoxybenzyl)-7H-purine-2,6-diamine 
• 1448464-69-4 6-chloro-9-(2-isopropyl-4,5-dimethoxybenzyl)-9H-purin-2-amine 
• 74385-35-6 2,3-bis(3',4'-diacetoxyphenyl)-2,3-dimethylbutane 
• 74385-32-3 C₁₈H₂₂O₄ 
• 412048-38-5 3,4-dimethoxycumyloxy radical 
• 412048-32-9 tert-butyl 3,4-dimethoxycumyl peroxide 

Relevant articles and documents

Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists

Ligands that selectively block P2X3 receptors localized on nociceptive sensory fibres may be useful for the treatment of chronic pain conditions including neuropathic pain, migraine, and inflammatory pain. With the aim at exploring the suitability of aden

Spectral properties and absolute rate constants for β-scission of ring-substituted cumyloxyl radicals. A laser flash photolysis study

A laser flash photolysis study of the spectral properties and β-scission reactions of a series of ring-substituted cumyloxyl radicals has been carried out. All cumyloxyl radicals display a broad absorption band in the visible region of the spectrum, which decays on the microsecond time scale, leading to a strong increase in absorption in the UV region of the spectrum, which is attributed to the corresponding acetophenone formed after β-scission of the cumyloxyl radicals. The position of the visible absorption band is red-shifted by the presence of electron-donating ring substituents, while a blue-shift is observed in the presence of electron-withdrawing ring substituents, suggesting that + R ring substituents promote charge separation in the excited cumyloxyl radical through stabilization of the partial positive charge on the aromatic ring of an incipient radical zwitterion. Along this line, an excellent Hammett-type correlation between the experimentally measured energies at the visible absorption maxima of the cumyloxyl radicals and σ+ substituent constants is obtained. A red-shift is also observed on going from MeCN to MeCN/H2O for all cumyloxyl radicals, pointing toward a specific effect of water. The ring substitution does not influence to a significant extent the rate constants for β-scission of the cumyloxyl radicals, which varies between 7.1 × 105 and 1.1 × 106 s-1, a result that suggests that cumyloxyl radical β-scission is not governed by the stability of the resulting acetophenone. Finally, κβ increases on going from MeCN to the more polar MeCN/H2O 1:1 for all cumyloxyl radicals, an observation that reflects the increased stabilization of the transition state for β-scission through increased solvation of the incipient acetophenone product.

2-SACCHARINYLMETHYL PHOSPHATES, PHOSPHONATES AND PHOSPHINATES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND COMPOSITIONS AND METHOD OF USE THEREOF

4-R 1-R 2-R 3-2-Saccharinylmethyl and 4,7-C-4,5, 6,7-tetrahydro-2-saccharinylmethyl phosphates, phosphonates and phosphinates of formulas I and IIA respectively herein, useful in the treatment of degenerative diseases, and compositions containing them, methods for using them to treat degenerative diseases, and processes for their preparation by reaction of the corresponding 2-halomethylsaccharins with a phosphate, phosphonate or phosphinic acid of formula III herein in the presence of an acid-acceptor.