744253-37-0 Usage
General Description
4-Pyrimidinecarboxylic acid, 6-chloro-2-methyl-, ethyl ester, also known under the CAS Number 85391-59-7, is a chemical compound belonging to the pyrimidines category. As suggested by its name, it has chlorine and methyl groups as substituents on the pyrimidine ring and also has a carboxylic acid functional group which is esterified with an ethyl group. Pyrimidines are important in numerous biological applications, such as DNA and RNA synthesis. The full specifications, details regarding its safety, potential hazards, or reactions with other substances for this chemical would be found in its Material Safety Data Sheet (MSDS).
Check Digit Verification of cas no
The CAS Registry Mumber 744253-37-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,4,2,5 and 3 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 744253-37:
(8*7)+(7*4)+(6*4)+(5*2)+(4*5)+(3*3)+(2*3)+(1*7)=160
160 % 10 = 0
So 744253-37-0 is a valid CAS Registry Number.
744253-37-0Relevant articles and documents
Synthesis of benzoylpyrimidines as antagonists of the corticotropin- releasing factor-1 receptor
Webb, Thomas R.,Moran, Terry,Huang, Charles Q.,McCarthy, James R.,Grigoriadis, Dimitri E.,Chen, Chen
, p. 3869 - 3873 (2004)
A series of benzoylpyrimidines derived from the anilinepyrimidine CRF 1 antagonists were synthesized. Several synthetic routes were developed to explore the SAR of this series of compounds. Compounds such as 8d (Ki=15nM) exhibited high binding affinities at the human CRF 1 receptor.
