74494-52-3

Basic information

• Product Name: 3-PIPERIDINE ACETIC ACID
• Synonyms: 3-Piperidineacetic Acid-d11;3-Piperidinylacetic acid;NSC 138735;2-(Piperidin-3-yl)
• CAS NO: 74494-52-3
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.19
• Mol File: 74494-52-3.mol
• Article Data: 1

Chemical Properties

• Melting Point: 276-278 °C
• Boiling Point: 286.8 °C at 760 mmHg
• Flash Point: 127.3 °C
• Appearance: /
• Density: 1.063 g/cm³
• Vapor Pressure: 0.000659mmHg at 25°C
• Refractive Index: 1.465
• Storage Temp.: 2-8°C
• Solubility: DCM, Methanol, Water
• PKA: 4.43±0.10(Predicted)
• CAS DataBase Reference: 3-PIPERIDINE ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PIPERIDINE ACETIC ACID(74494-52-3)
• EPA Substance Registry System: 3-PIPERIDINE ACETIC ACID(74494-52-3)

Safety Data

• Hazardous Substances Data: 74494-52-3(Hazardous Substances Data)

Usage

Description

3-PIPERIDINE ACETIC ACID, also known as 3-piperidinoacetic acid, is an organic compound with the chemical formula C6H11NO2. It features a piperidine ring attached to an acetic acid group, making it a derivative of both piperidine and acetic acid. 3-PIPERIDINE ACETIC ACID is known for its potential role as a GABA analog, which is significant in the study of synaptic transmission and inhibition.

Uses

Used in Neuroscientific Research:
3-PIPERIDINE ACETIC ACID is used as a GABA analog for studying synaptosome inhibition. Its structural similarity to GABA allows researchers to investigate the mechanisms of synaptic transmission and the role of GABAergic systems in the central nervous system.
Used in Pharmaceutical Development:
3-PIPERIDINE ACETIC ACID is used as a lead compound in the development of new pharmaceuticals targeting the GABAergic system. Its potential as a GABA analog makes it a valuable tool for designing drugs that can modulate inhibitory neurotransmission, which may have therapeutic applications in treating neurological disorders and conditions related to imbalances in excitatory and inhibitory signaling.
Used in Isotope Labeling Studies:
Isotope labeled 3-PIPERIDINE ACETIC ACID is used as a tracer in biochemical and pharmacological research. The incorporation of isotopes allows for the tracking of the compound's distribution, metabolism, and interaction with biological targets, providing valuable insights into its mechanism of action and potential applications in medicine.

InChI:InChI=1/C7H13NO2/c9-7(10)4-6-2-1-3-8-5-6/h6,8H,1-5H2,(H,9,10)

Downstream Products

• 73579-06-3 3-(2-hydroxyethyl)piperidine 
• 183483-09-2 2-(1-(tert-butoxycarbonyl)piperidin-3-yl)acetic acid 
• 115909-93-8 (+)-(R)-1-(Benzyloxycarbonyl)piperidin-3-ethanol 
• 115909-95-0 (+)-(R)-1-(Benzyloxycarbonyl)piperidin-3-propionitril 
• 115909-94-9 (+)-(R)-1-(Benzyloxycarbonyl)piperidin-3-ethhyl p-Toluolsulfonat 
• 115909-92-7 (+)-(R)-Piperidin-3-ethanol 
• 86827-10-3 benzyl 3-carboxymethylpiperidine-1-carboxylate 
• 1265322-06-2 2-(1-(2-hydroxy-2-(4-(5-(5-phenyl-4-propylisoxazol-3-yl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)piperidin-3-yl)acetic acid 

Relevant articles and documents

Tricyclic compounds

Novel compounds of Formula STR1 are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of the formula to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.