7450-57-9

Basic information

• Product Name: 3-AMINO-4-HYDROXYBENZOIC ACID
• Synonyms: TIMTEC-BB SBB006740;3-AMINO-4-HYDROXY-BENZOIC ACID HYDRAZIDE;3-AMINO-4-HYDROXYBENZOYL HYDRAZINE;3-AMINO-4-HYDROXYBENZHYDRAZIDE;4-HYDROXY-3-AMINOBENZOIC ACID;BENZOIC ACID, 3-AMINO-4-HYDROXY-
• CAS NO: 7450-57-9
• Molecular Formula: C₇H₉N₃O₂
• Molecular Weight: 153.14
• EINECS: 216-390-2
• Product Categories: Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes
• Mol File: 7450-57-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 208 °C (dec.)(lit.)
• Appearance: /
• Density: 1.42g/cm³
• Refractive Index: 1.688
• BRN: 6503217
• CAS DataBase Reference: 3-AMINO-4-HYDROXYBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-4-HYDROXYBENZOIC ACID(7450-57-9)
• EPA Substance Registry System: 3-AMINO-4-HYDROXYBENZOIC ACID(7450-57-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 7450-57-9(Hazardous Substances Data)

Usage

General Description

3-Amino-4-hydroxybenzoic acid, also known as 3-Amino-4-hydroxybenzoic acid or 3,4-Dihydroxyaniline, is an organic compound with the molecular formula C7H7NO3. It is a derivative of benzoic acid and is commonly used in the synthesis of pharmaceuticals and dyes. This chemical compound has a white crystalline appearance and is soluble in hot water. It is also used as an intermediate in the production of various dyes, and as a substitute for urea-formaldehyde resins in the manufacture of laminated products. Additionally, 3-Amino-4-hydroxybenzoic acid has potential applications in the field of medicine, particularly in the development of antiviral and anticancer drugs.

InChI:InChI=1/C7H9N3O2/c8-5-3-4(7(12)10-9)1-2-6(5)11/h1-3,11H,8-9H2,(H,10,12)

Upstream product

• 536-25-4 methyl 3-amino-4-hydroxybenzoate 

Downstream Products

• 807628-31-5 C₃₁H₃₄N₆O₆Si 
• 192862-31-0 (2Z,4E)-5-{(S)-4-[(3-Azido-4-hydroxy-benzoyl)-hydrazono]-1-hydroxy-2,6,6-trimethyl-cyclohex-2-enyl}-3-methyl-penta-2,4-dienoic acid 

Relevant articles and documents

Novel self-dyed wholly aromatic polyamide-hydrazides covalently bonded with azo groups in their main chains: 1. structure-property relationships

Twelve novel intrinsically colored wholly aromatic azopolyamide-hydrazides containing various proportions of para- and meta-phenylene units were successfully synthesized by a low temperature (-10 °C) solution polycondensation reaction of either 4-Amino-3-hydroxybenzhydrazide (4A3HBH) or 3-Amino-4-hydroxybenzhydrazide (3A4HBH) with an equimolar amount of either 4,4'-Azodibenzoyl chloride (4,4'ADBC), 3,3'-Azodibenzoyl chloride (3,3'ADBC), or mixtures of various molar ratios of 4,4'ADBC and 3,3'ADBC in anhydrous N,N-dimethyl acetamide (DMAc) containing 3% (wt/v) LiCl as a solvent. The structures of the polymers were proven by elemental analysis, FTIR, 1H- and 13C-NMR spectroscopy. The polymers' properties were strongly affected by their various structures. The intrinsic viscosities of the polymers were ranged from 0.7 to 4.75 dL g-1 and increased with the para-phenylene units content. The polymers are partially soluble in DMAc, dimethyl formamide (DMF) and N-methyl-2-pyrrolidone (NMP). Their solubility increases with the introduction of meta-phenylene moieties into the polymer chains. The polymers exhibit a great affinity for water sorption. Their hydrophilicity increases as a function of the content of meta-phenylene rings incorporated into the polymer. Mechanical properties of the polymer films are improved markedly by substitution of para-phenylene units for meta-phenylene units. The completely para-oriented type polymer has the best thermal and thermo-oxidative stability relative to those of the other polymers.

Glucagon antagonists/inverse agonists

Non-peptide compounds comprising a central hydrazide motif and methods for the synthesis thereof are disclosed. The compounds act to antagonize the action of the glucagon peptide hormone.

Methods for glycosylation inhibition using amino-benzoic acids and derivatives

The present invention relates to compounds, compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises an agent capable of inhibiting the formation of advanced glycosylation endproducts of target proteins by reacting with a carbonyl moiety of the early glycosylation product of such target proteins formed by their initial glycosylation. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.