74530-04-4

Basic information

• Product Name: 1-(4,6-dimethylpyrimidin-2-yl)urea
• Synonyms: 1-(4,6-Dimethylpyrimidin-2-yl)urea; Methanol, 1-[(4,6-dimethyl-2-pyrimidinyl)amino]-1-imino-; N-(4,6-Dimethylpyrimidin-2-yl)carbamimidic acid; Urea, N-(4,6-dimethyl-2-pyrimidinyl)-
• CAS NO: 74530-04-4
• Molecular Formula: C₇H₁₀N₄O
• Molecular Weight: 166.1805
• Mol File: 74530-04-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 348.4°C at 760 mmHg
• Flash Point: 164.5°C
• Density: 1.291g/cm³
• Vapor Pressure: 1.89E-05mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 1-(4,6-dimethylpyrimidin-2-yl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4,6-dimethylpyrimidin-2-yl)urea(74530-04-4)
• EPA Substance Registry System: 1-(4,6-dimethylpyrimidin-2-yl)urea(74530-04-4)

Safety Data

• Hazardous Substances Data: 74530-04-4(Hazardous Substances Data)

Upstream product

• 55474-90-3 (4,6-dimethylpyrimidin-2-yl)cyanamide 
• 141-83-3 carbamimidoylurea 
• 123-54-6 acetylacetone 
• 4472-44-0 2-chloro-4,6-dimethylpyrimidine 
• 88078-58-4 [(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]sulfamoyl chloride 
• 767-15-7 2-Amino-4,6-dimethylpyrimidine 

Downstream Products

• 16018-61-4 1-(4-chloro-phenyl)-3-(4,6-dimethyl-pyrimidin-2-yl)-urea 

Relevant articles and documents

One pot synthesis of hetero/aryl-urea derivatives: Chlorosulfonyl isocyanate, in situ hydrolysis method

An interesting approach for the direct and general synthesis of primary hetero/aryl urea compounds from corresponding amines. The highly efficient synthesis of mono-substituted hetero-aryl urea compounds by using chlorosulfonyl isocyanate followed by hydrolysis provides the corresponding urea in high yield and purity in reliable reaction conditions. Total 13 derivatives (4a-4m) were successfully synthesized by this approach and characterized. These were more interesting as further preparation of more cyclized compounds in use of drug and agro discoveries. Copyright