74531-16-1

Basic information

• Product Name: 3-Isoxazolecarboxamide,N,N,5-trimethyl-(9CI)
• Synonyms: 3-Isoxazolecarboxamide,N,N,5-trimethyl-(9CI);5-methyl-isoxazole-3-carboxylic acid dimethylamide
• CAS NO: 74531-16-1
• Molecular Formula: C7H10N2O2
• Molecular Weight: 154.1665
• Product Categories: OXAZOLE
• Mol File: 74531-16-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Isoxazolecarboxamide,N,N,5-trimethyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Isoxazolecarboxamide,N,N,5-trimethyl-(9CI)(74531-16-1)
• EPA Substance Registry System: 3-Isoxazolecarboxamide,N,N,5-trimethyl-(9CI)(74531-16-1)

Safety Data

• Hazardous Substances Data: 74531-16-1(Hazardous Substances Data)

Usage

General Description

3-Isoxazolecarboxamide, N,N,5-trimethyl-(9CI) is a chemical compound with the molecular formula C9H12N2O2. It is a derivative of isoxazolecarboxamide, containing a trimethyl group at the N,N,5 positions. 3-Isoxazolecarboxamide,N,N,5-trimethyl-(9CI) has potential pharmaceutical applications and may be used in research and development for the synthesis of new drugs or bioactive molecules. Its precise uses and properties would depend on further research and testing, as well as regulatory approval for specific applications.

Upstream product

• 39499-34-8 5-methyl-3-isoxazolyl chloride 
• 506-59-2 N,N-dimethylammonium chloride 
• 19788-35-3 methyl 5-methylisoxazole-3-carboxylate 
• 124-40-3 dimethyl amine 
• 20577-61-1 methyl 2,4-dioxopentanoate 

Downstream Products

• 60148-37-0 5-methyl-3-(N,N-dimethylaminomethyl) isoxazole 

Relevant articles and documents

Regioisomeric 3-, 4- and 5-aminomethyl isoxazoles: Synthesis and muscarinic activity

A series of 3-, 4- and 5-aminomethyl isoxazoles and isoxazoles with one or two additional methyl groups at the heterocycle were synthesized in order to investigate the structural requirements, ie heterocyclic moiety, regiochemistry and length of an aminoalkyl unit, for muscarinic activity. This was assayed on isolated rabbit vas deferens (M1 receptor subtype) and isolated guinea-pig atrium (M2 receptor subtype) and ileum (M3 receptor subtype). The isoxazoles tested are one to three orders of magnitude less active than furane or oxadiazole derivatives, having similar structural characteristics except for the heterocycle. Thus, the differences in molecular point charges and charge distribution contribute to the muscarinic activity of these compounds more than small differences in molecular shape and conformational energies.