74532-85-7 Usage
Description
(R)-1-(2-bromophenyl)propan-1-ol, also known as 2-bromophenylpropan-1-ol, is a chiral chemical compound with the molecular formula C9H11BrO. It is characterized by its non-superimposable mirror image, existing in two enantiomeric forms (R) and (S). (R)-1-(2-broMophenyl)propan-1-ol is soluble in organic solvents and can participate in various chemical reactions, such as oxidation and esterification. Due to its potential hazards, it should be handled with care in a controlled laboratory environment.
Uses
Used in Organic Synthesis:
(R)-1-(2-bromophenyl)propan-1-ol is used as a key intermediate in the organic synthesis of various compounds, including pharmaceuticals, agrochemicals, and perfumes. Its unique structure and reactivity make it a valuable building block for creating complex molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, (R)-1-(2-bromophenyl)propan-1-ol is used as an intermediate for the production of various drugs. Its chiral nature allows for the creation of enantiomerically pure compounds, which can have different biological activities and are essential in drug development.
Used in Agrochemicals:
(R)-1-(2-bromophenyl)propan-1-ol is also utilized in the agrochemical industry as an intermediate for the synthesis of pesticides and other agricultural chemicals. Its versatility in chemical reactions enables the development of new compounds with improved efficacy and selectivity.
Used in Perfumery:
In the perfume industry, (R)-1-(2-bromophenyl)propan-1-ol is used as a starting material for the synthesis of various fragrance components. Its ability to undergo chemical transformations allows for the creation of a wide range of scent molecules.
Used in Stereochemistry Research:
(R)-1-(2-bromophenyl)propan-1-ol has potential applications in the study of stereochemistry, which is the branch of chemistry that deals with the three-dimensional arrangement of atoms in molecules. Its chiral nature makes it an ideal candidate for investigating the effects of molecular geometry on chemical reactions and biological activities.
Used in Drug Candidate Development:
Due to its unique structural features, (R)-1-(2-bromophenyl)propan-1-ol is also used in the development of new drug candidates. Its potential applications in this area include the creation of novel therapeutic agents with improved pharmacological properties and reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 74532-85-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,5,3 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 74532-85:
(7*7)+(6*4)+(5*5)+(4*3)+(3*2)+(2*8)+(1*5)=137
137 % 10 = 7
So 74532-85-7 is a valid CAS Registry Number.
74532-85-7Relevant articles and documents
The intramolecular reaction of acetophenoneN-tosylhydrazone and vinyl: Br?nsted acid-promoted cationic cyclization toward polysubstituted indenes
Wang, Zhixin,Li, Yang,Chen, Fan,Qian, Peng-Cheng,Cheng, Jiang
, p. 1810 - 1813 (2021/02/27)
In the presence of TsNHNH2, a Br?nsted acid-promoted intramolecular cyclization ofo-(1-arylvinyl) acetophenone derivatives was developed, leading to polysubstituted indenes with complexity and diversity in moderate to excellent yields. In sharp contrast with either the radical or carbene involved cyclization of aldehydicN-tosylhydrazone with vinyl, a cationic cyclization pathway was involved, whereN-tosylhydrazone served as an electrophile and alkylation reagent during this transformation.
Asymmetric Synthesis and Application of Chiral Spirosilabiindanes
Chang, Xin,Chen, Hong-Chao,Li, Chuan-Ying,Ma, Pei-Long,Wang, Peng
supporting information, p. 8937 - 8940 (2020/04/30)
Reported here is the development of a class of chiral spirosilabiindane scaffolds by Rh-catalyzed asymmetric double hydrosilation, for the first time. Enantiopure SPSiOL (spirosilabiindane diol), a new type of chiral building block for the preparation of various chiral ligands and catalysts, was readily prepared on greater than 10 gram scale using this protocol. The potential of this new spirosilabiindane scaffold in asymmetric catalysis was preliminarily demonstrated by development of the corresponding monodentate phosphoramidite ligands (SPSiPhos), which were used in both a Rh-catalyzed hydrogenation and a Pd-catalyzed intramolecular carboamination.
Synthesis of fluorenyl alcohols: Via cooperative palladium/norbornene catalysis
Casnati, Alessandra,Fontana, Marco,Motti, Elena,Della Ca, Nicola
, p. 6165 - 6173 (2019/07/04)
Herein, we report a novel catalytic synthesis of substituted 9H-fluoren-9-ols starting from aryl iodides and secondary ortho-bromobenzyl alcohols in the presence of palladium/norbornene as a catalytic system. The present protocol exhibits high functional
