74575-44-3

Basic information

• Product Name: 6-methyl-5H-[1,3]dioxolo[4,5-f]indole
• Synonyms: 6-methyl-5H-[1,3]dioxolo[4,5-f]indole
• CAS NO: 74575-44-3
• Molecular Weight: 175.187
• Mol File: 74575-44-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-methyl-5H-[1,3]dioxolo[4,5-f]indole(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-5H-[1,3]dioxolo[4,5-f]indole(74575-44-3)
• EPA Substance Registry System: 6-methyl-5H-[1,3]dioxolo[4,5-f]indole(74575-44-3)

Safety Data

• Hazardous Substances Data: 74575-44-3(Hazardous Substances Data)

Upstream product

• 5434-47-9 5-bromo-6-bromomethylbenzo[1,3]dioxole 
• 1338460-64-2 (3-(6-bromobenzo[d][1,3]dioxol-5-yl)prop-1-yn-1-yl)-trimethylsilane 
• 1338460-73-3 5-bromo-6-(propa-1,2-dien-1-yl)benzo[d][1,3]dioxole 
• 55-21-0 benzamide 
• 7470-44-2 safrole 2',3'-oxide 

Downstream Products

• 113535-22-1 2-benzoylamino-3-(5,6-dimethyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)-propionic acid 
• 111272-56-1 4-(5,6-dimethyl-5H-[1,3]dioxolo[4,5-f]indol-7-ylmethylene)-2-phenyl-4H-oxazol-5-one 
• 99004-71-4 7-[1-(2,3-dimethoxy-phenyl)-2-nitro-ethyl]-6-methyl-5H-[1,3]dioxolo[4,5-f]indole 

Relevant articles and documents

Ortho-Bromo(propa-1,2-dien-1-yl)arenes: Substrates for domino reactions

o-Bromo(propa-1,2-dien-1-yl)arenes exhibit novel and orthogonal reactivity under Pd catalysis in the presence of secondary amines to form enamines (concerted Pd insertion, intramolecular carbopalladation, and terminative Buchwald-Hartwig coupling) and of amides to form indoles (addition, Buchwald-Hartwig cyclization, and loss of the acetyl group). The substrates for these reactions can be accessed in a reliable and highly selective two-step process from 2-bromoaryl bromides.