74581-07-0

Basic information

• Product Name: α-hydroxy-N-α',α'-dimethylphenylacetylglycine
• CAS NO: 74581-07-0
• Molecular Weight: 237.255
• Mol File: 74581-07-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: α-hydroxy-N-α',α'-dimethylphenylacetylglycine(CAS DataBase Reference)
• NIST Chemistry Reference: α-hydroxy-N-α',α'-dimethylphenylacetylglycine(74581-07-0)
• EPA Substance Registry System: α-hydroxy-N-α',α'-dimethylphenylacetylglycine(74581-07-0)

Safety Data

• Hazardous Substances Data: 74581-07-0(Hazardous Substances Data)

Upstream product

• 826-54-0 2-methyl-2-phenyl-propanamide 
• 298-12-4 Glyoxilic acid 

Downstream Products

• 74581-09-2 N-(α,α-dimethylphenylacetyl)phenylglycine 

Relevant articles and documents

INTRA VS INTERMOLECULAR AMIDOALKILATION OF AROMATICS

Three tipes of intramolecular amidoalkylation reactions of aromatics, two endotrigonal and one exotrigonal (I, II, III), leading to indolone, N-acylisoquinolines, isoquinolone and benzazepinone derivatives were studied.In the presence of external aromatic nucleophiles competing intermolecular amidoalkylations were observed (1->2, 13->14).The mechanism and the synthetic limitations of the three types of cyclization is discussed.