74597-79-8

Basic information

• Product Name: ETHYL 4-ACETYL-3-METHYL-5-(METHYLTHIO)THIOPHENE-2-CARBOXYLATE
• Synonyms: ETHYL 4-ACETYL-3-METHYL-5-(METHYLTHIO)THIOPHENE-2-CARBOXYLATE
• CAS NO: 74597-79-8
• Molecular Formula: C₁₁H₁₄O₃S₂
• Molecular Weight: 258.35706
• Mol File: 74597-79-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 75-76 °C(Solv: methanol (67-56-1))
• Boiling Point: 380.2±42.0 °C(Predicted)
• Appearance: /
• Density: 1.24±0.1 g/cm3(Predicted)
• CAS DataBase Reference: ETHYL 4-ACETYL-3-METHYL-5-(METHYLTHIO)THIOPHENE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 4-ACETYL-3-METHYL-5-(METHYLTHIO)THIOPHENE-2-CARBOXYLATE(74597-79-8)
• EPA Substance Registry System: ETHYL 4-ACETYL-3-METHYL-5-(METHYLTHIO)THIOPHENE-2-CARBOXYLATE(74597-79-8)

Safety Data

• Hazardous Substances Data: 74597-79-8(Hazardous Substances Data)

Upstream product

• 74597-98-1 ethyl 4-acetyl-5-mercapto-3-methylthiophen-2-carboxylate 
• 74-88-4 methyl iodide 
• 15908-50-6 3-[di(methylthio)methylene]pentane-2,4-dione 
• 105-36-2 ethyl bromoacetate 
• 623-51-8 ethyl 2-sulfanylacetate 
• 123-54-6 acetylacetone 
• 623-73-4 diazoacetic acid ethyl ester 

Downstream Products

• 74597-87-8 4-acetyl-3-methyl-5-methylthiothiophen-2-carboxylic acid 
• 175202-57-0 ethyl 5-cyano-3,4-dimethylthieno[2,3-b]thiophene-2-carboxylate 
• 152487-69-9 diethyl 3,4-dimethylthieno<2,3-b>thiophen-2,5-dicarboxylate 
• 74597-88-9 (E)-methyl (4-methyl-2-methylthio-3-thienyl) O-p-nitrobenzoylketoxime 
• 74597-84-5 C₁₉H₂₁NO₅S₂ 
• 74597-83-4 (E)-methyl (5-ethoxycarbonyl-4-methyl-2-methylthio-3-thienyl) O-p-nitrobenzoylketoxime 

Relevant articles and documents

4-alkylthio polysubstituted thiophene derivative and synthesis thereof

The invention discloses a method for synthesizing a 4-alkylthio polysubstituted thiophene derivative with potential biological activity. According to the invention, the 4-alkylthio polysubstituted thiophene derivative is generated in one step through intermolecular in-situ generation of sulfur ylide and intramolecular cyclization reaction by using a 3,3-dialkylthiomethylene-1,3-dicarbonyl compoundwith characteristics of easy preparation, structural diversity and multiple reaction centers and a diazo compound as raw materials, has a certain potential pharmaceutical activity, and can be furtherconverted into a functional product. The method has the advantages of easily available raw materials, simple operation, mild synthesis reaction conditions, high reaction efficiency, and diversity offunctional groups.

Copper(II)-catalyzed Domino Reaction of the Acyclic Ketene-(S,S)-Acetals with Diazo Compounds: Convenient Synthesis of Poly-substituted Thiophenes

Copper(II)-catalyzed domino reaction between the acyclic ketene-(S,S)-acetals and diazo compounds has been successfully developed. This reaction proceeds through a sequential formation of electrophilic copper carbenoid, sulfur ylide and subsequent C?S bon

Substituted isoxazolylthiophene compounds

This invention provides a substituted isoxazolylthiophene compound represented by the formula wherein R1and R2individually represent an alkyl group of 1-5 carbon atoms, R3represents a cyano group or a group CONR5R6(in which R5and R6individually represent a hydrogen atom or an alkyl group of 1-10 carbon atoms), R4represents an alkyl group of 1-5 carbon atoms or a phenyl group, and n is an integer of 0-2, or a salt thereof. The compounds of the invention are useful for the treatment or prevention of various bone diseases or nerve diseases, because they specifically enhance the action of the cell differentiation induction factors found in a living body.