7461-24-7 Usage
General Description
(1E)-2,3-dihydro-1H-inden-1-one semicarbazone, also known as 2,3-indandione semicarbazone, is a compound with the chemical formula C9H12N2O. It is a semicarbazone derivative of 2,3-indandione, which is a cyclic ketone. The compound is an off-white to yellow crystalline powder and is sparingly soluble in water. It is commonly used in organic synthesis as a reagent for the preparation of various heterocyclic compounds. Additionally, (1E)-2,3-dihydro-1H-inden-1-one semicarbazone exhibits potential pharmacological activities, including antimicrobial and anti-inflammatory properties. The compound has also been studied for its potential use as a therapeutic agent for various diseases. Overall, (1E)-2,3-dihydro-1H-inden-1-one semicarbazone is a versatile compound with important applications in both chemical synthesis and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 7461-24-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,6 and 1 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7461-24:
(6*7)+(5*4)+(4*6)+(3*1)+(2*2)+(1*4)=97
97 % 10 = 7
So 7461-24-7 is a valid CAS Registry Number.
7461-24-7Relevant articles and documents
Evaluation of the semicarbazones, thiosemicarbazones and bis-carbohydrazones of some aryl alicyclic ketones for anticonvulsant and other biological properties
Dimmock, J. R.,Pandeya, S. N.,Quail, J. W.,Pugazhenthi, U.,Allen, T. M.,et al.
, p. 303 - 314 (1995)
A number of aryl alicyclic ketones were converted to their corresponding semicarbazones, thiosemicarbazones and bis-carbohydrazones.Anticonvulsant activity was displayed by most of the compounds in the maximal electroshock (MES) and subcutaneous pentylenetetrazole (scPTZ) screens when given intraperitoneally to mice.However, on oral administration to rats, a marked selective activity in the MES screen only was noted.X-ray crystallography on five semicarbazones was undertaken in order to find correlations between the shapes of these molecules and anticonvulsant properties.The thiosemicarbazones displayed greater cytotoxicity to P388D1 and L1210 cells than the semicarbazones while a number of human tumors and different viruses were, in general, insensitive to representative compounds.semicarbazone/ thiosemicarbazone/ anticonvulsant agent/ X-ray crystallography/ cytotoxic agent
