7466-73-1

Basic information

• Product Name: 2-HYDROXY-10H-ACRIDIN-9-ONE
• Synonyms: Nsc402750
• CAS NO: 7466-73-1
• Molecular Formula: C13H9NO2
• Molecular Weight: 211.22
• Mol File: 7466-73-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 409.4 °C at 760 mmHg
• Flash Point: 201.4 °C
• Appearance: /
• Density: 1.345 g/cm³
• Vapor Pressure: 2.75E-07mmHg at 25°C
• Refractive Index: 1.677
• CAS DataBase Reference: 2-HYDROXY-10H-ACRIDIN-9-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXY-10H-ACRIDIN-9-ONE(7466-73-1)
• EPA Substance Registry System: 2-HYDROXY-10H-ACRIDIN-9-ONE(7466-73-1)

Safety Data

• Hazardous Substances Data: 7466-73-1(Hazardous Substances Data)

Usage

General Description

2-HYDROXY-10H-ACRIDIN-9-ONE is a chemical compound with the molecular formula C13H9NO2. It is a derivative of acridine, a nitrogen-containing polycyclic aromatic hydrocarbon. 2-HYDROXY-10H-ACRIDIN-9-ONE is commonly used in various applications, including as a fluorescent dye and in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential antimicrobial, antitumor, and antiviral properties. 2-HYDROXY-10H-ACRIDIN-9-ONE is known for its bright yellow-green fluorescence and is used in fluorescence microscopy and as a pH indicator in acidic solutions. It is important to handle this compound with care, as it may be toxic and harmful if ingested or inhaled.

InChI:InChI=1/C13H9NO2/c15-8-5-6-12-10(7-8)13(16)9-3-1-2-4-11(9)14-12/h1-7,15H,(H,14,16)

Upstream product

• 75843-49-1 2-ethoxy-9-chloro-acridine 
• 61556-11-4 9-acridone-2-sulfonic acid 
• 13278-33-6 N-p-ethoxyphenylanthranilic acid 
• 13501-67-2 N-(p-methoxyphenyl)anthranilic acid 
• 49742-72-5 2-methoxy-9(10H)-acridinone 
• 104-94-9 4-methoxy-aniline 
• 118-91-2 ortho-chlorobenzoic acid 
• 578-95-0 10H-acridin-9-one 
• 91-40-7 2-(phenylamino)benzoic acid 

Downstream Products

• 49742-72-5 2-methoxy-9(10H)-acridinone 
• 22817-17-0 acridin-2-ol 
• 1370524-12-1 10-benzyloxycarbonyl-2-(benzyloxycarbonyl)oxy-9,10-dihydroacridine 

Relevant articles and documents

Sulfonic acid-catalyzed autoxidative carbon-carbon coupling reaction under elevated partial pressure of oxygen

An aerobic organocatalytic oxidative C-C bond formation reaction of benzylic C-H bonds with various C-nucleophiles is described. The coupling reaction proceeds by simply stirring the substrates under elevated partial pressure of oxygen in the presence of a sulfonic acid catalyst at room temperature. Elevation of the pressure enables the reaction of a broad scope of nucleophile substrates otherwise showing poor reactivity at ambient pressure. The benzylic C-H bonds of xanthene, acridanes, isochromane and related heterocycles could be functionalized with nucleophiles including ketones, 1,3-dicarbonyl compounds and aldehydes. Electron-rich arenes could be utilized as nucleophiles at elevated temperatures. The reactions are believed to proceed via autoxidation of the benzylic C-H bonds to the hydroperoxides and subsequent nucleophilic substitution catalyzed by sulfonic acids. Copyright

Acridone derivatives: Design, synthesis, and inhibition of breast cancer resistance protein ABCG2

The breast cancer resistance protein (BCRP, ABCG2) is among the latest discovered ABC proteins to be involved in MDR phenotype and for which only few inhibitors are known. In continuing our program aimed at discovering efficient multidrug resistance modul