74696-68-7

Basic information

• Product Name: N-(4-trifluoroacetyl-phenyl)-isobutyramide
• Synonyms: N-(4-trifluoroacetyl-phenyl)-isobutyramide
• CAS NO: 74696-68-7
• Molecular Weight: 259.228
• Mol File: 74696-68-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-trifluoroacetyl-phenyl)-isobutyramide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-trifluoroacetyl-phenyl)-isobutyramide(74696-68-7)
• EPA Substance Registry System: N-(4-trifluoroacetyl-phenyl)-isobutyramide(74696-68-7)

Safety Data

• Hazardous Substances Data: 74696-68-7(Hazardous Substances Data)

Upstream product

• 144459-68-7 α,α-bis(trifluoromethyl)-4-nitrobenzylalkohol 
• 619-50-1 4-nitrobenzoic acid methyl ester 
• 23516-79-2 4-(trifluoroacetyl)aniline 
• 79-30-1 isobutyryl chloride 

Relevant articles and documents

Novel trifluoroacetophenone derivatives as malonyl-CoA decarboxylase inhibitors

A series of trifluoroacetophenone derivatives were prepared and evaluated as malonyl-CoA decarboxylase (MCD) inhibitors. Some of the 'reverse amide' analogs were found to be potent inhibitors of MCD enzyme activity. The trifluoroacetyl group may interact with the MCD active site as the hydrate in a similar fashion to the hexafluoroisopropanol analogs reported previously. Adding electron-withdrawing groups to the phenyl ring stabilizes the hydrated species and enhances this interaction.