7470-14-6Relevant articles and documents
Ultrafast Photoclick Reaction for Selective18F-Positron Emission Tomography Tracer Synthesis in Flow
Fu, Youxin,Helbert, Hugo,Simeth, Nadja A.,Crespi, Stefano,Spoelstra, Gerbren B.,van Dijl, Jan Maarten,van Oosten, Marleen,Nazario, Luiza Reali,van der Born, Dion,Luurtsema, Gert,Szymanski, Wiktor,Elsinga, Philip H.,Feringa, Ben L.
supporting information, p. 10041 - 10047 (2021/07/21)
The development of very fast, clean, and selective methods for indirect labeling in PET tracer synthesis is an ongoing challenge. Here we present the development of an ultrafast photoclick method for the synthesis of short-lived18F-PET tracers
COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING PTEN INHIBITORS
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Paragraph 0326, (2018/12/13)
This invention is directed to, inter alia, compounds, methods, systems, and compositions for the maintenance, enhancement, and expansion of hematopoietic stem cells derived from sources of non-mobilized peripheral blood. Also provided herein are compounds of Formula I which are useful in maintaining, enhancing, and expanding of hematopoietic stem cells.
Preparation of polycyclic azaarenes by an extended Pomeranz-Fritsch procedure
Hewlins, Michael J. E.,Salter, Rhys
, p. 2157 - 2163 (2008/03/28)
An extension of the Pomeranz-Fritsch procedure has been evaluated as a route to some polycyclic azaarenes. Aromatic aldehydes were treated with the dimethyl and diethyl acetals of 2-aminoethanal, the resulting imines reduced to amines which were tosylated and the resulting sulfonamides treated under a range of acidic conditions. The two naphthaldehydes led to benzo[f]isoquinoline and benzo[h]isoquinoline in overall yields of 13% and 36%. Phenanthrene-9- carbaldehyde and phenanthrene-3-carbaldehyde gave dibenzo[f,h]isoquinoline and naphtho[2,1-g]isoquinoline, respectively, as the major tetracyclic products. No pentacyclic product was obtained from a similar sequence starting from pyrene-1-carbaldehyde. Georg Thieme Verlag Stuttgart.