7471-58-1

Basic information

• Product Name: 2(1H)-Quinazolinone (6CI,8CI,9CI)
• Synonyms: 2(1H)-Quinazolinone (6CI,8CI,9CI);1,2-Dihydroquinazoline-2-one;2(3H)-Quinazolinone;Quinazoline-2-ol;Quinazolin-2(1H)-one;2(1H)-Quinazolinone;1H-Quinazolin-2-one
• CAS NO: 7471-58-1
• Molecular Formula: C₈H₆N₂O
• Molecular Weight: 146.146
• Product Categories: PYRIMIDINE
• Mol File: 7471-58-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 250 °C
• Boiling Point: 395 °Cat760mmHg
• Flash Point: 192.7 °C
• Appearance: /
• Density: 1.31 g/cm³
• Vapor Pressure: 8.33E-07mmHg at 25°C
• Refractive Index: 1.666
• Storage Temp.: 2-8°C
• PKA: 12.40±0.20(Predicted)
• CAS DataBase Reference: 2(1H)-Quinazolinone (6CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Quinazolinone (6CI,8CI,9CI)(7471-58-1)
• EPA Substance Registry System: 2(1H)-Quinazolinone (6CI,8CI,9CI)(7471-58-1)

Safety Data

• Hazardous Substances Data: 7471-58-1(Hazardous Substances Data)

Usage

General Description

2(1H)-Quinazolinone is a heterocyclic chemical compound with the molecular formula C8H6N2O. It is a derivative of quinazoline and is a bicyclic compound with a quinazolin-4(3H)-one core. It is commonly used as a building block in the synthesis of various organic compounds and pharmaceuticals. It has also shown potential pharmacological activities, including anti-inflammatory, anti-cancer, and anti-viral properties. Additionally, it is being studied for its potential application in the treatment of neurological disorders and as an anti-depressant. Overall, 2(1H)-Quinazolinone is a versatile chemical with diverse applications and potential therapeutic benefits.

InChI:InChI=1/C8H6N2O/c11-8-9-5-6-3-1-2-4-7(6)10-8/h1-5H,(H,9,10,11)

Downstream Products

• 1026-04-6 2-(2'-hydroxyphenyl)-4-(3H)-quinazolinone 
• 112888-43-4 4(3H)-oxo-6-(bromomethyl)-2-methyl quinazoline 
• 253-82-7 quinazoline 
• 150877-33-1 6-Acetyl-4-ethyl-3,4-dihydro-3-methyl-4-phenylquinazolin-2(1H)-one 
• 66655-67-2 1,2,3,4-tetrahydroquinazolin-2-one 

Relevant articles and documents

Enzymatic analysis using substrates that yield fluorescent precipitates

Novel fluorescent precipitating substrates made from a class of fluorophores, generally including quinazolinones (quinazolones), benzimidazoles, benzothiazoles, benzoxazoles, quinolines, indolines, and phenanthridines, having the general formula: STR1 where carbon atoms of --C1 =C2 -- are further joined so as to complete a first 5- or 6-membered aromatic ring which may contain at least one of the hetero atoms N, O or S, where carbon atoms of --C4 --N=C3 -- are further joined so as to complete a second 5- or 6-membered aromatic ring that contains at least the nitrogen between C3 and C4 and may contain at least one additional hetero atom N, O or S, where the first and second aromatic rings may be joined by a 5- or 6-membered bridging ring that contains at least the C2 from the first aromatic ring and the C3 from the second aromatic ring, which bridging ring may be saturated or unsaturated and may contain a hetero atom N, O, or S, where each of the first and second aromatic rings may be fused to at least one additional aromatic ring that may contain at least one of the hetero atoms N, O or S, and where each of said aromatic rings may be further modified by substitution of any hydrogens on an aromatic carbon by substituents that are halogen, nitro, cyano, aryl, lower alkyl (1-4 carbons), perfluoroalkyl (1-4 carbons), or alkoxy (1-4 carbons), or any combination thereof; and Xfl is covalently linked to the oxygen --O-- at C1.