7474-15-9

Basic information

• Product Name: (2E)-2-(hydroxyimino)-1,1-diphenylpropan-1-ol
• CAS NO: 7474-15-9
• Molecular Formula: C₁₅H₁₅NO₂
• Molecular Weight: 241.2851
• Mol File: 7474-15-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 446.083°C at 760 mmHg
• Flash Point: 292.057°C
• Density: 1.093g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.563
• CAS DataBase Reference: (2E)-2-(hydroxyimino)-1,1-diphenylpropan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-2-(hydroxyimino)-1,1-diphenylpropan-1-ol(7474-15-9)
• EPA Substance Registry System: (2E)-2-(hydroxyimino)-1,1-diphenylpropan-1-ol(7474-15-9)

Safety Data

• Hazardous Substances Data: 7474-15-9(Hazardous Substances Data)

Usage

General Description

"(2E)-2-(hydroxyimino)-1,1-diphenylpropan-1-ol" is a chemical compound with the molecular formula C15H15NO2. It has a hydroxyimino functional group, which makes it a member of the oxime class of compounds. This molecule consists of a diphenylpropanol backbone with a hydroxyimino group attached to the second carbon of the chain. The (2E) in the name indicates the positioning of the double bond in the molecule. (2E)-2-(hydroxyimino)-1,1-diphenylpropan-1-ol may have potential applications in organic synthesis, pharmaceuticals, or other industrial uses, and it is important for researchers to study its properties and reactivity.

Upstream product

• 4571-02-2 1-hydroxy-1,1-diphenyl-2-propanone 
• 119-51-7 1-phenyl-1,2-propanedione 2-oxime 
• 781-35-1 1,1-diphenylacetone 
• 33718-91-1 1,1-diphenyl-1-bromo-2-propanone 
• 3923-52-2 1,1-diphenyl-2-propyn-1-ol 

Downstream Products

• 102839-77-0 (2-Isopropyl-aziridin-2-yl)-diphenyl-methanol 
• 64889-90-3 (2-ethyl-aziridin-2-yl)diphenylmethanol 
• 64889-89-0 diphenyl(2-phenyl-aziridin-2-yl)methanol 
• 102839-82-7 5-Isopropyl-4,4-diphenyl-3-oxa-1-aza-bicyclo[3.1.0]hexan-2-one 
• 25683-83-4 2,3,3-triphenylacrylaldehyde 
• 89030-17-1 3-Ethyl-2,2-diphenyl-1-aza-bicyclo[1.1.0]butane 
• 89030-16-0 2,2,3-triphenyl-1-azabicyclo<1.1.0>butane 
• 64890-05-7 5-Ethyl-4,4-diphenyl-3-oxa-1-aza-bicyclo[3.1.0]hexan-2-one 
• 64890-04-6 4,4,5-Triphenyl-3-oxa-1-aza-bicyclo[3.1.0]hexan-2-one 
• 102839-81-6 Carbonic acid diphenyl-(2-phenyl-aziridin-2-yl)-methyl ester ethyl ester 

Relevant articles and documents

A rare ligand bridged ferromagnetically coupled MnIV3 complex with a ground spin state of S = 9/2

An exclusively chelating ligand bridged high-valent [MnIV 3] complex has been synthesized, in which all MnIV ions are ferromagnetically-coupled to exhibit an ST = 9/2 spin ground state. The Royal Society of Chem

Intermolecular Cope-type hydroamination of alkenes and alkynes using hydroxylamines

The development of the Cope-type hydroamination as a method for the metal- and acid-free intermolecular hydroamination of hydroxylamines with alkenes and alkynes is described. Aqueous hydroxylamine reacts efficiently with alkynes in a Markovnikov fashion to give oximes and with strained alkenes to give N-alkylhydroxylamines, while unstrained alkenes are more challenging. N-Alkylhydroxy-lamines also display similar reactivity with strained alkenes and give modest to good yields with vinylarenes. Electron-rich vinylarenes lead to branched products while electron-deficient vinylarenes give linear products. A beneficial additive effect is observed with sodium cyanoborohydride, the extent of which is dependent on the structure of the hydroxylamine. The reaction conditions are found to be compatible with common protecting groups, free OH and NH bonds, as well as bromoarenes. Both experimental and theoretical results suggest the proton transfer step of the N-oxide intermediate is of vital importance in the intermolecular reactions of alkenes. Details are disclosed concerning optimization, reaction scope, limitations, and theoretical analysis by DFT, which includes a detailed molecular orbital description for the concerted hydroamination process and an exhaustive set of calculated potential energy surfaces for the reactions of various alkenes, alkynes, and hydroxylamines.