7474-80-8

Basic information

• Product Name: 3-methoxy-N,N-dimethyl-4-nitrosoaniline
• CAS NO: 7474-80-8
• Molecular Formula: C₉H₁₂N₂O₂
• Molecular Weight: 180.2038
• Mol File: 7474-80-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 309.1°C at 760 mmHg
• Flash Point: 140.7°C
• Density: 1.08g/cm³
• Vapor Pressure: 0.000654mmHg at 25°C
• Refractive Index: 1.517
• CAS DataBase Reference: 3-methoxy-N,N-dimethyl-4-nitrosoaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methoxy-N,N-dimethyl-4-nitrosoaniline(7474-80-8)
• EPA Substance Registry System: 3-methoxy-N,N-dimethyl-4-nitrosoaniline(7474-80-8)

Safety Data

• Hazardous Substances Data: 7474-80-8(Hazardous Substances Data)

Upstream product

• 15799-79-8 3-methoxy-N,N-dimethylaniline 
• 7647-01-0 hydrogenchloride 

Relevant articles and documents

Synthesis and antimalarial property of orally active phenoxazinium salts

Phenoxazinium salts were found to display good antimalarial efficacy in vivo against Plasmodium berghei. Several compounds provided 100% parasitemia clearance at a dose of 20-30 mg kg-1 x 4 days (ip) and good survival effects without obvious acute toxicity. They also showed excellent potency by oral administration. A preliminary pharmacokinetic study revealed that the oral availability of 1a was excellent.